Universität zu Köln

Fuchs, Hans Friedrich, Babic, Benjamin, Fuchs, Karl-Hermann, Breithaupt, Wolfram, Varga, Gabor and Musial, Frauke (2019). Do patients with gastroesophageal reflux disease and somatoform tendencies benefit from antireflux surgery? World J. Gastroenterol., 25 (3). S. 388 - 398. PLEASANTON: BAISHIDENG PUBLISHING GROUP INC. ISSN 2219-2840

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Abstract

BACKGROUND The clinical presentation of gastroesophageal reflux disease (GERD) shows a large symptom variation also in different intensities among patients. As several studies have shown, there is a large overlap in the symptomatic spectrum between proven GERD and other disorders such as dyspepsia, functional heartburn and/or somatoform disorders. AIM To prospectively evaluate the GERD patients with and without somatoform disorders before and after laparoscopic antireflux surgery. METHODS In a tertiary referral center for foregut surgery over a period of 3 years patients with GERD, qualifying for the indication of laparoscopic antireflux surgery, were investigated prospectively regarding their symptomatic spectrum in order to identify GERD and associated somatoform disorders. Assessment of symptoms was performed by an instrument for the evaluation of somatoform disorders [Somatoform Symptom Index (SSI) > 17]. Quality of life was evaluated by Gastrointestinal Quality of Life Index (GIQLI). RESULTS In 123 patients an indication for laparoscopic antireflux surgery was established and in 43 patients further medical therapy was suggested. The portion of somatoform tendencies in the total patient population was 20.48% (34 patients). Patients with a positive SSI had a preoperative GIQLI of 77 (32-111). Patients with a normal SSI had a GIQLI of 105 (29-140) (P < 0.0001). In patients with GERD the quality of life could be normalized from preoperative reduced values of GIQLI 102 (47-140) to postoperative values of 1.17 (44-144). In patients with GERD and somatoform disorders, the GIQLI was improved from preoperative GIQLI 75 (47-111) to postoperative 95 (44-122) (P < 0.0043). CONCLUSION Patients with GERD and associated somatoform disorders have significantly worse levels of quality of life. The latter patients can also benefit from laparoscopic fundoplication, however they will not reach a normal level.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Fuchs, Hans Friedrich UNSPECIFIED UNSPECIFIED UNSPECIFIED Babic, Benjamin UNSPECIFIED UNSPECIFIED UNSPECIFIED Fuchs, Karl-Hermann UNSPECIFIED UNSPECIFIED UNSPECIFIED Breithaupt, Wolfram UNSPECIFIED UNSPECIFIED UNSPECIFIED Varga, Gabor UNSPECIFIED UNSPECIFIED UNSPECIFIED Musial, Frauke UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-159067
DOI:	10.3748/wjg.v25.i3.388
Journal or Publication Title:	World J. Gastroenterol.
Volume:	25
Number:	3
Page Range:	S. 388 - 398
Date:	2019
Publisher:	BAISHIDENG PUBLISHING GROUP INC
Place of Publication:	PLEASANTON
ISSN:	2219-2840
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language FUNCTIONAL DYSPEPSIA; PRIMARY-CARE; SYMPTOMS; SOMATIZATION; DEPRESSION; STRESS; CLASSIFICATION; PERSONALITY; ASSOCIATION; PREVALENCE Multiple languages Gastroenterology & Hepatology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/15906