Universität zu Köln

Sharma, Shachi Jenny, Wagner, Steffen, Reder, Henrike Simone Frauke, Kroll, Tobias, Wuerdemann, Nora, Klussmann, Jens Peter and Wittekindt, Claus ORCID: 0000-0003-1696-0199 (2018). The 8th edition AJCC/UICC TNM staging for p16-positive oropharyngeal carcinoma: is there space for improvement? Eur. Arch. Oto-Rhino-Laryn., 275 (12). S. 3087 - 3092. NEW YORK: SPRINGER. ISSN 1434-4726

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Abstract

The 8th edition of the AJCC/UICC TNM-staging system for p16[HPV]-positive OPSCC manages to improve prediction of prognosis and will essentially influence choice of therapy in future. Nonetheless, adjustments of the current version are needed. The surrogate marker p16 alone is inadequate for HPV detection, the role of ECS in HPV-positive OPSCC is not fully understood, and the patient's characteristics as well as molecular signatures and genetics have not been taken into consideration yet.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Sharma, Shachi Jenny UNSPECIFIED UNSPECIFIED UNSPECIFIED Wagner, Steffen UNSPECIFIED UNSPECIFIED UNSPECIFIED Reder, Henrike Simone Frauke UNSPECIFIED UNSPECIFIED UNSPECIFIED Kroll, Tobias UNSPECIFIED UNSPECIFIED UNSPECIFIED Wuerdemann, Nora UNSPECIFIED UNSPECIFIED UNSPECIFIED Klussmann, Jens Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Wittekindt, Claus UNSPECIFIED orcid.org/0000-0003-1696-0199 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-163653
DOI:	10.1007/s00405-018-5156-4
Journal or Publication Title:	Eur. Arch. Oto-Rhino-Laryn.
Volume:	275
Number:	12
Page Range:	S. 3087 - 3092
Date:	2018
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1434-4726
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language HUMAN-PAPILLOMAVIRUS; EXTRACAPSULAR SPREAD; ICON-S; CANCER; HPV; PROGNOSTICATOR; VALIDATION; PREDICTOR; SURVIVAL; HEAD Multiple languages Otorhinolaryngology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/16365