Woeckel, Achim, Festl, Jasmin, Stueber, Tanja, Brust, Katharina, Krockenberger, Mathias, Heuschmann, Peter U., Jiru-Hillmann, Steffi, Albert, Ute-Susann, Budach, Wilfried, Follmann, Markus ORCID: 0000-0003-3790-5578, Janni, Wolfgang, Kopp, Ina, Kreienberg, Rolf, Kuehn, Thorsten, Langer, Thomas, Nothacker, Monika, Scharl, Anton, Schreer, Ingrid, Link, Hartmut, Engel, Jutta, Fehm, Tanja, Weis, Joachim, Welt, Anja, Steckelberg, Anke, Feyer, Petra, Koenig, Klaus, Hahne, Andrea, Baumgartner, Traudl, Kreipe, Hans H., Knoefel, Wolfram Trudo, Denkinger, Michael ORCID: 0000-0002-8097-060X, Brucker, Sara, Lueftner, Diana, Kubisch, Christian ORCID: 0000-0003-4220-0978, Gerlach, Christina, Lebeau, Annette, Siedentopf, Friederike, Petersen, Cordula, Bartsch, Hans Helge, Schulz-Wendtland, Rudiger, Hahn, Markus, Hanf, Volker, Mueller-Schimpfle, Markus, Henscher, Ulla, Roncarati, Renza, Katalinic, Alexander ORCID: 0000-0003-0490-1554, Heitmann, Christoph, Honegger, Christoph, Paradies, Kerstin, Bjelic-Radisic, Vesna, Degenhardt, Friedrich, Wenz, Frederik, Rick, Oliver, Hoelzel, Dieter, Zaiss, Matthias, Kemper, Gudrun, Budach, Volker, Denkert, Carsten, Gerber, Bernd, Tesch, Hans, Hirsmueller, Susanne, Sinn, Hans-Peter ORCID: 0000-0003-2836-6699, Dunst, Juergen, Muenstedt, Karsten, Bick, Ulrich, Fallenberg, Eva, Tholen, Reina, Hung, Roswita, Baumann, Freerk, Beckmann, MatthiasW., Blohmer, Jens, Fasching, Peter, Lux, Michael P., Harbeck, Nadia, Hadji, Peyman, Hauner, Hans, Heywang-Koebrunner, Sylvia, Huober, Jens, Huebner, Jutta, Jackisch, Christian, Loibl, Sibylle, Lueck, Hans-Juergen, von Minckwitz, Gunter, Moebus, Volker, Mueller, Volkmar, Noethlings, Ute, Schmidt, Marcus ORCID: 0000-0003-1365-2414, Schmutzler, Rita, Schneeweiss, Andreas, Schuetz, Florian, Stickeler, Elmar, Thomssen, Christoph, Untch, Michael, Wesselmann, Simone, Buecker, Arno, Buck, Andreas and Stangl, Stephanie ORCID: 0000-0002-5177-8635 (2018). Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032/045OL, December 2017) - Part 2 with Recommendations for the Therapy of Primary, Recurrent and Advanced Breast Cancer. Geburtshilfe Frauenheilkd., 78 (11). S. 1056 - 1089. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1438-8804

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Abstract

Purpose The aim of this official guideline coordinated and published by the German Society for Gynecology and Obstetrics (DGGG) and the German Cancer Society (DKG) was to optimize the screening, diagnosis, therapy and follow-up care of breast cancer. Method The process of updating the S3 guideline published in 2012 was based on the adaptation of identified source guidelines. They were combined with reviews of evidence compiled using PICO (Patients/Interventions/Control/Outcome) questions and with the results of a systematic search of literature databases followed by the selection and evaluation of the identified literature. The interdisciplinary working groups took the identified materials as their starting point and used them to develop suggestions for recommendations and statements, which were then modified and graded in a structured consensus process procedure. Recommendations Part 2 of this short version of the guideline presents recommendations for the therapy of primary, recurrent and metastatic breast cancer. Loco-regional therapies are de-escalated in the current guideline. In addition to reducing the safety margins for surgical procedures, the guideline also recommends reducing the radicality of axillary surgery. The choice and extent of systemic therapy depends on the respective tumor biology. New substances are becoming available, particularly to treat metastatic breast cancer.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Woeckel, AchimUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Festl, JasminUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stueber, TanjaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Brust, KatharinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Krockenberger, MathiasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Heuschmann, Peter U.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jiru-Hillmann, SteffiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Albert, Ute-SusannUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Budach, WilfriedUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Follmann, MarkusUNSPECIFIEDorcid.org/0000-0003-3790-5578UNSPECIFIED
Janni, WolfgangUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kopp, InaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kreienberg, RolfUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kuehn, ThorstenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Langer, ThomasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nothacker, MonikaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Scharl, AntonUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schreer, IngridUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Link, HartmutUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Engel, JuttaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fehm, TanjaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Weis, JoachimUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Welt, AnjaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Steckelberg, AnkeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Feyer, PetraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Koenig, KlausUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hahne, AndreaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Baumgartner, TraudlUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kreipe, Hans H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Knoefel, Wolfram TrudoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Denkinger, MichaelUNSPECIFIEDorcid.org/0000-0002-8097-060XUNSPECIFIED
Brucker, SaraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lueftner, DianaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kubisch, ChristianUNSPECIFIEDorcid.org/0000-0003-4220-0978UNSPECIFIED
Gerlach, ChristinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lebeau, AnnetteUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Siedentopf, FriederikeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Petersen, CordulaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bartsch, Hans HelgeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schulz-Wendtland, RudigerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hahn, MarkusUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hanf, VolkerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mueller-Schimpfle, MarkusUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Henscher, UllaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Roncarati, RenzaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Katalinic, AlexanderUNSPECIFIEDorcid.org/0000-0003-0490-1554UNSPECIFIED
Heitmann, ChristophUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Honegger, ChristophUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Paradies, KerstinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bjelic-Radisic, VesnaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Degenhardt, FriedrichUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wenz, FrederikUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rick, OliverUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hoelzel, DieterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Zaiss, MatthiasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kemper, GudrunUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Budach, VolkerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Denkert, CarstenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gerber, BerndUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tesch, HansUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hirsmueller, SusanneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sinn, Hans-PeterUNSPECIFIEDorcid.org/0000-0003-2836-6699UNSPECIFIED
Dunst, JuergenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Muenstedt, KarstenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bick, UlrichUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fallenberg, EvaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tholen, ReinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hung, RoswitaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Baumann, FreerkUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Beckmann, MatthiasW.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Blohmer, JensUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fasching, PeterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lux, Michael P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Harbeck, NadiaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hadji, PeymanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hauner, HansUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Heywang-Koebrunner, SylviaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Huober, JensUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Huebner, JuttaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jackisch, ChristianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Loibl, SibylleUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lueck, Hans-JuergenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
von Minckwitz, GunterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Moebus, VolkerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mueller, VolkmarUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Noethlings, UteUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schmidt, MarcusUNSPECIFIEDorcid.org/0000-0003-1365-2414UNSPECIFIED
Schmutzler, RitaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schneeweiss, AndreasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schuetz, FlorianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stickeler, ElmarUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Thomssen, ChristophUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Untch, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wesselmann, SimoneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Buecker, ArnoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Buck, AndreasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stangl, StephanieUNSPECIFIEDorcid.org/0000-0002-5177-8635UNSPECIFIED
URN: urn:nbn:de:hbz:38-166901
DOI: 10.1055/a-0646-4630
Journal or Publication Title: Geburtshilfe Frauenheilkd.
Volume: 78
Number: 11
Page Range: S. 1056 - 1089
Date: 2018
Publisher: GEORG THIEME VERLAG KG
Place of Publication: STUTTGART
ISSN: 1438-8804
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
SURGICAL ADJUVANT BREAST; PHASE-III TRIAL; DOXORUBICIN PLUS CYCLOPHOSPHAMIDE; CLINICAL-PRACTICE GUIDELINES; POSTMASTECTOMY RADIATION-THERAPY; RANDOMIZED CONTROLLED-TRIAL; NIPPLE-SPARING MASTECTOMY; CONGESTIVE-HEART-FAILURE; WHOLE-BRAIN RADIOTHERAPY; ESTROGEN-RECEPTOR STATUSMultiple languages
Obstetrics & GynecologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/16690

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