Universität zu Köln

Stankevich, Yuliya, Lueken, Ulrike, Balzer-Geldsetzer, Monika, Dodel, Richard, Graeber-Sultan, Susanne, Berg, Daniela, Liepelt-Scarfone, Inga, Hilker-Roggendorf, Ruediger, Kalbe, Elke, Kaut, Oliver, Mollenhauer, Brit, Reetz, Kathrin, Schaeffer, Eva, Schmidt, Nele, Schulz, Joerg B., Spottke, Annika, Witt, Karsten, Linse, Katharina, Storch, Alexander and Riedel, Oliver (2018). Psychometric Properties of an Abbreviated Version of the Apathy Evaluation Scale for Parkinson Disease (AES-12PD). Am. J. Geriatr. Psychiatr., 26 (10). S. 1079 - 1091. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1545-7214

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Abstract

Background: Apathy is a frequent symptom in Parkinson's disease (PD), substantially aggravating the course of PD. Regarding the accumulating evidence of the key role of apathy in PD, time-efficient assessments are useful for fostering progress in research and treatment. The Apathy Evaluation Scale (AES) is widely used for the assessment of apathy across different nosologies. Objective: To facilitate the application of the AES in PD, we reduced the AES to two-thirds its length and validated this abbreviated version. Design: Data sets of 339 PD patients of the DEMPARK/LANDSCAPE study without dementia and depression were randomly split into two samples. Data of sample 1 were used to develop a brief version of the AES (AES-12PD). A cross-validation was conducted in sample 2 and in a subsample of 42 PD patients with comorbid dementia and depressive symptomatology. Receiver operating characteristic analysis was applied to determine the optimal cutoff of the AES-12PD as an indicator of apathy. Results: The AES-12PD featured high internal consistency that was better compared to the AES. The abbreviated scale was well differentiated from motor impairment and cognitive deficits. The AES-12PD cutoff of 27/28 was the optimal cutoff for apathy in PD patients without dementia and depression. The cutoff of 25/26 indicated apathy in PD patients with comorbid dementia and depression. Conclusion: Results confirm a high internal consistency and good discriminant validity of the AES-12PD. The AES-12PD represents a reliable tool for the efficient assessment of apathy that can be applied in PD patients with and without dementia and depression.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Stankevich, Yuliya UNSPECIFIED UNSPECIFIED UNSPECIFIED Lueken, Ulrike UNSPECIFIED UNSPECIFIED UNSPECIFIED Balzer-Geldsetzer, Monika UNSPECIFIED UNSPECIFIED UNSPECIFIED Dodel, Richard UNSPECIFIED UNSPECIFIED UNSPECIFIED Graeber-Sultan, Susanne UNSPECIFIED UNSPECIFIED UNSPECIFIED Berg, Daniela UNSPECIFIED UNSPECIFIED UNSPECIFIED Liepelt-Scarfone, Inga UNSPECIFIED UNSPECIFIED UNSPECIFIED Hilker-Roggendorf, Ruediger UNSPECIFIED UNSPECIFIED UNSPECIFIED Kalbe, Elke UNSPECIFIED UNSPECIFIED UNSPECIFIED Kaut, Oliver UNSPECIFIED UNSPECIFIED UNSPECIFIED Mollenhauer, Brit UNSPECIFIED UNSPECIFIED UNSPECIFIED Reetz, Kathrin UNSPECIFIED UNSPECIFIED UNSPECIFIED Schaeffer, Eva UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmidt, Nele UNSPECIFIED UNSPECIFIED UNSPECIFIED Schulz, Joerg B. UNSPECIFIED UNSPECIFIED UNSPECIFIED Spottke, Annika UNSPECIFIED UNSPECIFIED UNSPECIFIED Witt, Karsten UNSPECIFIED UNSPECIFIED UNSPECIFIED Linse, Katharina UNSPECIFIED UNSPECIFIED UNSPECIFIED Storch, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Riedel, Oliver UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-170065
DOI:	10.1016/j.jagp.2018.06.012
Journal or Publication Title:	Am. J. Geriatr. Psychiatr.
Volume:	26
Number:	10
Page Range:	S. 1079 - 1091
Date:	2018
Publisher:	ELSEVIER SCIENCE INC
Place of Publication:	NEW YORK
ISSN:	1545-7214
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CLINICAL DIAGNOSTIC-CRITERIA; ALZHEIMERS-DISEASE; DEMENTIA; DEPRESSION; RECOMMENDATIONS; VALIDATION; RELIABILITY; INSTRUMENT; SYMPTOMS; VALIDITY Multiple languages Geriatrics & Gerontology; Gerontology; Psychiatry Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/17006