Universität zu Köln

Haidl, Theresa, Rosen, Marlene, Schultze-Lutter, Frauke, Nieman, Dorien ORCID: 0000-0002-9846-4254, Eggers, Susanne, Heinimaa, Markus, Juckel, Georg, Heinz, Andreas ORCID: 0000-0001-5405-9065, Morrison, Anthony, Linszen, Don, Salokangas, Raimo, Klosterkoetter, Joachim, Birchwood, Max ORCID: 0000-0002-7476-0171, Patterson, Paul ORCID: 0000-0003-3310-8635 and Ruhrmann, Stephan ORCID: 0000-0002-6022-2364 (2018). Expressed emotion as a predictor of the first psychotic episode - Results of the European prediction of psychosis study. Schizophr. Res., 199. S. 346 - 353. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1573-2509

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Abstract

Objective: To investigate the impact of expressed emotion (EE) on the risk of developing the first psychotic episode (FEP). Method: The European Prediction of Psychosis Study (EPOS) investigated 245 patients who were at clinical high risk (CHR) of psychosis. The predictive value of EE alone and as a part of the multivariate EPOS model was evaluated. Results: Perceived irritability, a domain of the Level of Expressed Emotion Scale (LEE), was found to be predictive for the First Psychotic Episode (FEP), even as an individual variable. Furthermore, it was selected in the multivariate EPOS prediction model, thereby replacing two of the original predictor variables. This led to an improved revised version that enabled the identification of three significantly different risk classes with a hazard rate of up to 0.911. Conclusions: CHR subjects who perceive the most important person in their individual social environment to be limited in their stress coping skills had a higher risk of conversion to the first psychotic episode. The importance of this risk factor was further demonstrated by an improvement of risk estimation in the original EPOS predictor model. Perceiving a reference person as stress-prone and thus potentially unreliable might amplify self-experienced uncertainty and anxiety, which are often associated with the prodromal phase. Such an enforcement of stress-related processes could promote a conversion to psychosis. (c) 2018 Elsevier B.V. All rights reserved.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Haidl, Theresa UNSPECIFIED UNSPECIFIED UNSPECIFIED Rosen, Marlene UNSPECIFIED UNSPECIFIED UNSPECIFIED Schultze-Lutter, Frauke UNSPECIFIED UNSPECIFIED UNSPECIFIED Nieman, Dorien UNSPECIFIED orcid.org/0000-0002-9846-4254 UNSPECIFIED Eggers, Susanne UNSPECIFIED UNSPECIFIED UNSPECIFIED Heinimaa, Markus UNSPECIFIED UNSPECIFIED UNSPECIFIED Juckel, Georg UNSPECIFIED UNSPECIFIED UNSPECIFIED Heinz, Andreas UNSPECIFIED orcid.org/0000-0001-5405-9065 UNSPECIFIED Morrison, Anthony UNSPECIFIED UNSPECIFIED UNSPECIFIED Linszen, Don UNSPECIFIED UNSPECIFIED UNSPECIFIED Salokangas, Raimo UNSPECIFIED UNSPECIFIED UNSPECIFIED Klosterkoetter, Joachim UNSPECIFIED UNSPECIFIED UNSPECIFIED Birchwood, Max UNSPECIFIED orcid.org/0000-0002-7476-0171 UNSPECIFIED Patterson, Paul UNSPECIFIED orcid.org/0000-0003-3310-8635 UNSPECIFIED Ruhrmann, Stephan UNSPECIFIED orcid.org/0000-0002-6022-2364 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-174426
DOI:	10.1016/j.schres.2018.03.019
Journal or Publication Title:	Schizophr. Res.
Volume:	199
Page Range:	S. 346 - 353
Date:	2018
Publisher:	ELSEVIER SCIENCE BV
Place of Publication:	AMSTERDAM
ISSN:	1573-2509
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ULTRA-HIGH-RISK; CLINICAL HIGH-RISK; TERM-FOLLOW-UP; YOUNG-PEOPLE; SCHIZOPHRENIC-PATIENTS; 1ST-EPISODE PSYCHOSIS; CONTROLLED-TRIAL; DAILY-LIFE; LEE SCALE; AT-RISK Multiple languages Psychiatry Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/17442