Universität zu Köln

Jung, N. and Rieg, S. (2018). Essentials in the management of S-aureus bloodstream infection. Infection, 46 (4). S. 441 - 443. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1439-0973

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Abstract

Aims Staphylococcus aureus bloodstream infection is one of the most common serious bacterial infections worldwide. It represents a heterogenous clinical entity with a high risk of metastatic complications and a high in-hospital mortality ranging between 20 and 30%. The outcome can be improved by optimised diagnostic and therapeutic management. Thus, our minire-view should provide important and often missed pieces of information in the management of S. aureus bloodstream infection. Methods We describe the essentials in the management of S. aureus bloodstream infection. Results Five essentials were identified: 1) S. aureus bacteremia should always be considered clinically significant. 2) Length of bacteremia and fever is relevant for diagnostic workup, duration of therapy and prognosis. 3) Prompt identification and eradication of portal of entry and infective/metastatic foci are essential. 4) Infective endocarditis should be excluded. 5) Intravenous treatment for at least two weeks up to 4-6 weeks with antistaphylococcal penicillins for MSSA and vancomycin or daptomycin for MRSA bloodstream infection is indicated. Conclusion Further efforts should be undertaken to increase the adherence to the essentials in the management of S. aureus bloodstream infection.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Jung, N. UNSPECIFIED UNSPECIFIED UNSPECIFIED Rieg, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-178531
DOI:	10.1007/s15010-018-1130-8
Journal or Publication Title:	Infection
Volume:	46
Number:	4
Page Range:	S. 441 - 443
Date:	2018
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1439-0973
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language BACTEREMIA; DISEASES Multiple languages Infectious Diseases Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/17853