Universität zu Köln

Matsushige, T., Kraemer, M., Sato, T., Berlit, P., Forsting, M., Ladd, M. E., Jabbarli, R., Sure, U., Khan, N., Schlamann, M. and Wrede, K. H. (2018). Visualization and Classification of Deeply Seated Collateral Networks in Moyamoya Angiopathy with 7T MRI. Am. J. Neuroradiol., 39 (7). S. 1248 - 1255. DENVILLE: AMER SOC NEURORADIOLOGY. ISSN 1936-959X

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Abstract

This study aimed to evaluate morphologic patterns and the delineation of deeply seated collateral networks using ultra-high-field MRA in comparison with conventional DSA in 15 patients. Sequences acquired at 7T were TOF-MRA with 0.22 X 0.22 X 0.41 mm(3) resolution and MPRAGE with 0.7 X 0.7 X 0.7 mm(3) resolution. The relevant deeply seated collateral networks were classified into 2 categories and 6 pathways. A total of 100 collateral networks were detected on DSA; 106, on TOF-MRA; and 73, on MPRAGE. Delineation of deeply seated collateral networks was comparable between TOF-MRA and DSA. The authors demonstrate excellent delineation of 6 distinct deeply seated collateral network pathways in Moyamoya angiopathy. BACKGROUND AND PURPOSE: Collateral networks in Moyamoya angiopathy have a complex angioarchitecture difficult to comprehend on conventional examinations. This study aimed to evaluate morphologic patterns and the delineation of deeply seated collateral networks using ultra-high-field MRA in comparison with conventional DSA. MATERIALS AND METHODS: Fifteen white patients with Moyamoya angiopathy were investigated in this prospective trial. Sequences acquired at 7T were TOF-MRA with 0.22 x 0.22 x 0.41 mm(3) resolution and MPRAGE with 0.7 x 0.7 x 0.7 mm(3) resolution. Four raters evaluated the presence of deeply seated collateral networks and image quality in a consensus reading of DSA, TOF-MRA, and MPRAGE using a 5-point scale in axial source images and maximum intensity projections. Delineation of deeply seated collateral networks by different imaging modalities was compared by means of the McNemar test, whereas image quality was compared using the Wilcoxon signed-rank test. RESULTS: The relevant deeply seated collateral networks were classified into 2 categories and 6 pathways. A total of 100 collateral networks were detected on DSA; 106, on TOF-MRA; and 73, on MPRAGE. Delineation of deeply seated collateral networks was comparable between TOF-MRA and DSA (P = .25); however, both were better than MPRAGE (P < .001). CONCLUSIONS: This study demonstrates excellent delineation of 6 distinct deeply seated collateral network pathways in Moyamoya angiopathy in white adults using 7T TOF-MRA, comparable to DSA.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Matsushige, T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kraemer, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Sato, T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Berlit, P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Forsting, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Ladd, M. E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Jabbarli, R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Sure, U. UNSPECIFIED UNSPECIFIED UNSPECIFIED Khan, N. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schlamann, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wrede, K. H. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-181808
DOI:	10.3174/ajnr.A5700
Journal or Publication Title:	Am. J. Neuroradiol.
Volume:	39
Number:	7
Page Range:	S. 1248 - 1255
Date:	2018
Publisher:	AMER SOC NEURORADIOLOGY
Place of Publication:	DENVILLE
ISSN:	1936-959X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MAGNETIC-RESONANCE ANGIOGRAPHY; SUPERSELECTIVE ANGIOGRAPHY; PRELIMINARY EXPERIENCE; DISEASE; CIRCULATION; ARTERIES; TESLA; DIAGNOSIS; PATHOLOGY; EUROPEANS Multiple languages Clinical Neurology; Neuroimaging; Radiology, Nuclear Medicine & Medical Imaging Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/18180