Universität zu Köln

Dieplinger, G., Mokhaberi, N., Wahba, R., Peltzer, S., Buchner, D., Schloesser, H. A., Ditt, V, von Borstel, A., Bauerfeind, U., Lange, U., Arns, W., Kurschat, C., Stippel, H. A. and Vitinius, F. (2018). Correlation Between the Transplant Evaluation Rating Scale (TERS) and Medical Outcomes in Living-Donor Kidney Transplant Recipients: A Retrospective Analysis. Transplant. Proc., 50 (5). S. 1276 - 1281. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1873-2623

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Abstract

Background. Pretransplant psychosocial evaluation of living-donor kidney transplantation (LDKT) candidates identifies recipients with potentially inferior posttransplant outcomes. Rating instruments, based on semi-standardized interviews, help to improve and standardize psychosocial evaluation. The goal of this study was to retrospectively investigate the correlation between the Transplant Evaluation Rating Scale (TERS) and transplant outcome in LDKT recipients. Methods. TERS scores were retrospectively generated by 2 raters based on comprehensive interviews of 146 LDKT recipients conducted by mental health professionals (interrater reliability, 0.8-0.9). All patients were eligible for transplantation according to pretransplant psychosocial evaluation. Patients were classified into 2 groups according to their TERS scores, in either two thirds excellent risk (TERS <29) and one third at least moderate risk (TERS >= 29) candidates. Analyzed medical parameters were change in estimated glomerular filtration rate and acute rejection (AR) episodes within the first year posttransplant. In addition, a subgroup of 65 patients was tested for de novo donor-specific HLA antibodies (DSA) posttransplant. Results. There was no significant difference between the excellent (n = 97) and at least moderate (n = 49) risk candidates according to TERS in terms of organ function (estimated glomerular filtration rate decline >25%: 17 of 97 vs 11 of 49; P = .51) and episodes of AR (19 of 97 vs 15 of 49; P = .15). Patients developing de novo DSA (n = 18 [28%]) did not have higher pretransplant TERS scores (DSA positive, 11 of 42 vs 7 of 23; P = .78). Conclusions. Classifying LDKT recipients according to TERS score did not predict medical outcome at 1 year posttransplant or the occurrence of de novo DSA.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Dieplinger, G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Mokhaberi, N. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wahba, R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Peltzer, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Buchner, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schloesser, H. A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Ditt, V UNSPECIFIED UNSPECIFIED UNSPECIFIED von Borstel, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bauerfeind, U. UNSPECIFIED UNSPECIFIED UNSPECIFIED Lange, U. UNSPECIFIED UNSPECIFIED UNSPECIFIED Arns, W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kurschat, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Stippel, H. A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Vitinius, F. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-184027
DOI:	10.1016/j.transproceed.2018.02.082
Journal or Publication Title:	Transplant. Proc.
Volume:	50
Number:	5
Page Range:	S. 1276 - 1281
Date:	2018
Publisher:	ELSEVIER SCIENCE INC
Place of Publication:	NEW YORK
ISSN:	1873-2623
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ORGAN TRANSPLANT; PSYCHOSOCIAL EVALUATION; NONCOMPLIANCE; CANDIDATES; LUNG Multiple languages Immunology; Surgery; Transplantation Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/18402