Universität zu Köln

Ahmadzadehfar, H., Albers, P., Bockisch, A., Boegemann, M., Boehme, C., Burchert, W., Dietlein, M., Drzezga, A., Fabry, U., Feldmann, G., Heidenreich, A., Heinzel, A., Herrmann, K., Heyll, A., Hoehling, C., Kreuzer, C., Laufer, D., Mengel, R., Mottaghy, F. M., Mueller, H-W., Mueller, S. C., Ost, E., Rahbar, K., Reifenhaeuser, W., Schaefers, M., Schlenkhoff, C., Schmidt, M., Schmidt-Wolf, I., Wildenhain, C., Zimmer, B. and Essler, M. (2018). Lutetium-177-PSMA radioligand therapy. Consensus within the framework of GKV-funded care between the university hospitals in Aachen, Bonn, Dusseldorf, Essen, and Cologne and the MDK Nordrhein. Urologe, 57 (6). S. 709 - 714. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-0563

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Abstract

In the last 3 years, Lutetium-177 prostate-specific membrane antigen radioligand therapy (Lu-177-PSMA-RLT) has received increasing attention in nuclear medicine as a new form of treatment for castration-resistant metastatic prostate cancer. This therapy combines the radionuclide Lutetium-177, which has been therapeutically used in nuclear medicine for many years, with a molecular target of the transmembrane prostate-specific membrane antigen expressed by prostate cancer cells. Since there are no prospective randomized studies on Lu-177-PSMA-RLT and the question of reimbursement has repeatedly been the subject of review by the MDK Nordrhein (Medischenische Dienst der Krankenversicherung), there was a desire because of the increasing number of patients being treated to clarify under which circumstances Lu-177-PSMA-RLT can be reimbursed by German statutory health insurance. The goals of this article are to help treating physicians understand how this new therapy option works, to integrate it in the overall therapy concept for castration-resistant metastatic prostate cancer, and, above all, to use Lu-177-PSMA-RLT-based on the current data-at the right place in the therapy sequence of castration-resistant metastatic prostate cancer.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Ahmadzadehfar, H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Albers, P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bockisch, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Boegemann, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Boehme, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Burchert, W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Dietlein, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Drzezga, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Fabry, U. UNSPECIFIED UNSPECIFIED UNSPECIFIED Feldmann, G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Heidenreich, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Heinzel, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Herrmann, K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Heyll, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hoehling, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kreuzer, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Laufer, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Mengel, R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Mottaghy, F. M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Mueller, H-W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Mueller, S. C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Ost, E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Rahbar, K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Reifenhaeuser, W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schaefers, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schlenkhoff, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmidt, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmidt-Wolf, I. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wildenhain, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Zimmer, B. UNSPECIFIED UNSPECIFIED UNSPECIFIED Essler, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-184632
DOI:	10.1007/s00120-018-0642-2
Journal or Publication Title:	Urologe
Volume:	57
Number:	6
Page Range:	S. 709 - 714
Date:	2018
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1433-0563
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language RESISTANT PROSTATE-CANCER; LU-177-PSMA-617; CYCLES; PSMA Multiple languages Urology & Nephrology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/18463