Universität zu Köln

Thielker, Jovanna, Grosheva, Maria ORCID: 0000-0002-5985-468X, Ihrler, Stephan, Wittig, Andrea and Guntinas-Lichius, Orlando ORCID: 0000-0001-9671-0784 (2018). Contemporary Management of Benign and Malignant Parotid Tumors. Front. Surg., 5. LAUSANNE: FRONTIERS MEDIA SA. ISSN 2296-875X

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Abstract

Background: To report the standard of care, interesting new findings and controversies about the treatment of parotid tumors. Methods: Relevant and actual studies were searched in PubMed and reviewed for diagnostics, treatment and outcome of both benign and malignant tumors. Results: Prospective trials are lacking due to rarity of the disease and high variety of tumor subtypes. Conclusion: The establishment of reliable non-invasive diagnostics tools for the differentiation between benign and malignant tumors is desirable. Prospective studies clarifying the association between different surgical techniques for benign parotid tumors and morbidity are needed. The role of adjuvant or definitive radiotherapy in securing loco-regional control and improving survival in malignant disease is established. Prospective clinical trials addressing the role of chemotherapy/molecular targeted therapy for parotid cancer are needed. An international consensus on the classification of parotid surgery techniques would facilitate the comparison of different trials. Such efforts should lead into a clinical guideline.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Thielker, Jovanna UNSPECIFIED UNSPECIFIED UNSPECIFIED Grosheva, Maria UNSPECIFIED orcid.org/0000-0002-5985-468X UNSPECIFIED Ihrler, Stephan UNSPECIFIED UNSPECIFIED UNSPECIFIED Wittig, Andrea UNSPECIFIED UNSPECIFIED UNSPECIFIED Guntinas-Lichius, Orlando UNSPECIFIED orcid.org/0000-0001-9671-0784 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-186480
DOI:	10.3389/fsurg.2018.00039
Journal or Publication Title:	Front. Surg.
Volume:	5
Date:	2018
Publisher:	FRONTIERS MEDIA SA
Place of Publication:	LAUSANNE
ISSN:	2296-875X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SALIVARY-GLAND CARCINOMAS; ADENOID CYSTIC CARCINOMA; SQUAMOUS-CELL CARCINOMA; FINE-NEEDLE-ASPIRATION; CARBON ION THERAPY; RECURRENT PLEOMORPHIC ADENOMA; PARAPHARYNGEAL SPACE TUMORS; LYMPH-NODE METASTASES; CANCER DATA-BASE; EXTRACAPSULAR DISSECTION Multiple languages Surgery Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/18648