Universität zu Köln

Schaub, Friederike, Adler, Werner ORCID: 0000-0001-9791-5407, Enders, Philip ORCID: 0000-0002-9527-4957, Koenig, Meike C., Koch, Konrad R., Cursiefen, Claus, Kirchhof, Bernd and Heindl, Ludwig M. (2018). Preexisting epiretinal membrane is associated with pseudophakic cystoid macular edema. Graefes Arch. Clin. Exp. Ophthalmol., 256 (5). S. 909 - 918. NEW YORK: SPRINGER. ISSN 1435-702X

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Abstract

The purpose of the present study was to evaluate whether preexisting epiretinal membrane (ERM) is a significant risk factor for developing pseudophakic cystoid macular edema (PCME). Two hundred four consecutive eyes and 153 consecutive eyes without preexisting epiretinal membranes were retrospectively compared regarding PCME development following phacoemulsification with posterior chamber lens implantation. Patients with vascular retinal diseases, uveitis, trauma, neovascular macular degeneration, chronic inflammatory conditions, diabetic retinopathy, endophthalmitis, eventful cataract surgery, and combination of cataract surgery and vitrectomy during the observation period were excluded. Macular examination was performed using spectral-domain optical coherence tomography (SD-OCT) before as well as at 4, 8, 12, 16, 24, and 36 weeks after cataract surgery. Univariate and multivariate logistic regression analyses were calculated. PCME occurred in 32 of 204 eyes with preexisting ERM (15.7%), whereas 9 of 153 eyes without preexisting ERM (5.9%) developed PCME. The risk of PCME was significantly increased in eyes with ERM (p = 0.007). By multivariate logistic regression analysis, factors predictive of PCME included the history of previous pars plana vitrectomy for retinal detachment (odds ratio (OR) 3.619 [95% confidence interval (CI) 1.242 to 10.258]; p = 0.016) as well as the preexistence of ERM (OR 3.885 [95% CI 1.162 to 17.762]; p = 0.04). Preexisting ERM seems to be associated with an increased risk of PCME following cataract surgery. Therefore, this risk should be considered in surgery planning, preoperative medication, and follow-up care after surgery.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schaub, Friederike UNSPECIFIED UNSPECIFIED UNSPECIFIED Adler, Werner UNSPECIFIED orcid.org/0000-0001-9791-5407 UNSPECIFIED Enders, Philip UNSPECIFIED orcid.org/0000-0002-9527-4957 UNSPECIFIED Koenig, Meike C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Koch, Konrad R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Cursiefen, Claus UNSPECIFIED UNSPECIFIED UNSPECIFIED Kirchhof, Bernd UNSPECIFIED UNSPECIFIED UNSPECIFIED Heindl, Ludwig M. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-186924
DOI:	10.1007/s00417-018-3954-4
Journal or Publication Title:	Graefes Arch. Clin. Exp. Ophthalmol.
Volume:	256
Number:	5
Page Range:	S. 909 - 918
Date:	2018
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1435-702X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language OPTICAL COHERENCE TOMOGRAPHY; CATARACT-SURGERY; RISK-FACTORS; INTRACAMERAL INJECTION; PHACOEMULSIFICATION SURGERY; PSEUDOEXFOLIATION GLAUCOMA; TRABECULAR ASPIRATION; EYES; CEFUROXIME; ENDOPHTHALMITIS Multiple languages Ophthalmology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/18692