Universität zu Köln

Mellinghoff, Sibylle C., Hoenigl, Martin ORCID: 0000-0002-1653-2824, Koehler, Philipp ORCID: 0000-0002-7386-7495, Kumar, Anil, Lagrou, Katrien, Lass-Floerl, Cornelia, Meis, Jacques F., Menon, Vidya, Rautemaa-Richardson, Riina and Cornely, Oliver A. (2018). EQUAL Candida Score: An ECMM score derived from current guidelines to measure QUAlity of Clinical Candidaemia Management. Mycoses, 61 (5). S. 326 - 331. HOBOKEN: WILEY. ISSN 1439-0507

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Abstract

Candida species frequently cause blood stream infections and are reported to be the third to tenth most commonly isolated pathogens. Guidelines and standardised treatment algorithms provided by professional organisations aim to facilitate decision-making regarding diagnosis, management and treatment of candidaemia. In routine clinical practise, however, it may be challenging to comply with these guidelines. The reasons include lack of familiarity or feasibility to adherence, but also their length and complexity. There is no tool to measure guideline adherence currently. To provide such a tool, we reviewed the current guidelines provided by the European Society for Clinical Microbiology and Infectious Diseases (ESCMID) and by the Infectious Diseases Society of America (IDSA), and selected the strongest recommendations for management quality as the bases for our scoring tool. Factors incorporated were diagnostic (blood cultures, echocardiography, ophthalmoscopy, species identification) and follow-up procedures (repeat blood cultures until negative result) as well as key treatment parameters (echinocandin treatment, step down to fluconazole depending on susceptibility result, CVC removal). The EQUAL Candida Score weighs and aggregates factors recommended for the ideal management of candidaemia and provides a tool for antifungal stewardship as well as for measuring guideline adherence.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Mellinghoff, Sibylle C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hoenigl, Martin UNSPECIFIED orcid.org/0000-0002-1653-2824 UNSPECIFIED Koehler, Philipp UNSPECIFIED orcid.org/0000-0002-7386-7495 UNSPECIFIED Kumar, Anil UNSPECIFIED UNSPECIFIED UNSPECIFIED Lagrou, Katrien UNSPECIFIED UNSPECIFIED UNSPECIFIED Lass-Floerl, Cornelia UNSPECIFIED UNSPECIFIED UNSPECIFIED Meis, Jacques F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Menon, Vidya UNSPECIFIED UNSPECIFIED UNSPECIFIED Rautemaa-Richardson, Riina UNSPECIFIED UNSPECIFIED UNSPECIFIED Cornely, Oliver A. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-188530
DOI:	10.1111/myc.12746
Journal or Publication Title:	Mycoses
Volume:	61
Number:	5
Page Range:	S. 326 - 331
Date:	2018
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1439-0507
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language BLOOD-STREAM INFECTIONS; ESCMID-ASTERISK GUIDELINE; INVASIVE FUNGAL DISEASE; DOUBLE-BLIND TRIAL; ATTRIBUTABLE MORTALITY; NOSOCOMIAL CANDIDEMIA; EUROPEAN ORGANIZATION; ADULT PATIENTS; RISK-FACTORS; EPIDEMIOLOGY Multiple languages Dermatology; Mycology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/18853