Universität zu Köln

Baues, Christian, Rosenbrock, Johannes, Herfarth, Klaus, Lukas, Peter, Engenhart-Cabillic, Rita, Schmidtberger, Heinz, Marntiz, Simone and Eich, Hans Theodor (2018). Modern radiotherapy in Hodgkin's lymphoma. Onkologe, 24 (4). S. 295 - 303. NEW YORK: SPRINGER. ISSN 1433-0415

Full text not available from this repository.

Abstract

The treatment of mostly young patients with Hodgkin lymphoma (HL) in most cases leads to a permanent cure. Unlike no other disease, the continuous treatment of patients in clinical trials led to an ongoing optimization of therapy. The initial large field radiotherapy was reduced as well as the irradiation dosage and by the addition of chemotherapy the combined modality was established. A selective review of the available data on HL and radiotherapy was carried out based on the PubMed database. Current technical innovations and new target volume definitions strongly influence radiotherapy planning and execution more than ever. Due to the excellent prognosis of HL patients, long-term toxicity plays a pivotal role. Lung fibroses, cardiac infarction and secondary malignancies are possible side effects. Their risk can be influenced by a thorough radiotherapy planning and execution. Thus, techniques, such as deep inspiration breath hold (DIBH) and modern radiotherapy techniques, such as intensity modulated radiotherapy (IMRT) and image guided radiotherapy (IGRT) have a strong impact, very similar to the new target volume definitions of the International Lymphoma Radiation Oncology Group (ILROG). The use of improved techniques in radiotherapy planning and performance has made high precision radiotherapy feasible. Furthermore, current data suggest a positive influence on acute and long-term side effects.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Baues, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Rosenbrock, Johannes UNSPECIFIED UNSPECIFIED UNSPECIFIED Herfarth, Klaus UNSPECIFIED UNSPECIFIED UNSPECIFIED Lukas, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Engenhart-Cabillic, Rita UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmidtberger, Heinz UNSPECIFIED UNSPECIFIED UNSPECIFIED Marntiz, Simone UNSPECIFIED UNSPECIFIED UNSPECIFIED Eich, Hans Theodor UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-191861
DOI:	10.1007/s00761-018-0335-x
Journal or Publication Title:	Onkologe
Volume:	24
Number:	4
Page Range:	S. 295 - 303
Date:	2018
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1433-0415
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language INVOLVED-NODE RADIOTHERAPY; INTENSITY-MODULATED RADIOTHERAPY; CONFORMAL RADIATION-THERAPY; EORTC/LYSA/FIL H10 TRIAL; INSPIRATION BREATH-HOLD; FIELD RADIOTHERAPY; FEMALE-PATIENTS; PROTON THERAPY; FINAL ANALYSIS; CHEMOTHERAPY Multiple languages Oncology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/19186