Universität zu Köln

Jeppesen, Jesper ORCID: 0000-0002-3095-2040, Otto, Marit, Frederiksen, Yoon, Hansen, Allan K., Fedorova, Tatyana D., Knudsen, Karoline, Nahimi, Adjmal, Brooks, David J., Borghammer, Per ORCID: 0000-0001-6391-8052 and Sommerauer, Michael (2018). Observations on muscle activity in REM sleep behavior disorder assessed with a semi-automated scoring algorithm. Clin. Neurophysiol., 129 (3). S. 541 - 548. CLARE: ELSEVIER IRELAND LTD. ISSN 1872-8952

Full text not available from this repository.

Abstract

Objectives: Rapid eye movement (REM) sleep behavior disorder (RBD) is defined by dream enactment due to a failure of normal muscle atonia. Visual assessment of this muscle activity is time consuming and rater-dependent. Methods: An EMG computer algorithm for scoring 'tonic', 'phasic' and 'any' submental muscle activity during REM sleep was evaluated compared with human visual ratings. Subsequently, 52 subjects were analyzed with the algorithm. Duration and maximal amplitude of muscle activity, and self-awareness of RBD symptoms were assessed. Results: The computer algorithm showed high congruency with human ratings and all subjects with RBD were correctly identified by excess of submental muscle activity, when artifacts were removed before analysis. Subjects with RBD exhibited prolonged bouts of 'phasic' muscle activity with high amplitude. Self-awareness of RBD symptoms correlated with amount of REM sleep without atonia. Conclusions: Our proposed algorithm was able to detect and rate REM sleep without atonia allowing identification of RBD. Increased duration and amplitude of muscle activity bouts were characteristics of RBD. Quantification of REM sleep without atonia represents a marker of RBD severity. (C) 2017 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Jeppesen, Jesper UNSPECIFIED orcid.org/0000-0002-3095-2040 UNSPECIFIED Otto, Marit UNSPECIFIED UNSPECIFIED UNSPECIFIED Frederiksen, Yoon UNSPECIFIED UNSPECIFIED UNSPECIFIED Hansen, Allan K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Fedorova, Tatyana D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Knudsen, Karoline UNSPECIFIED UNSPECIFIED UNSPECIFIED Nahimi, Adjmal UNSPECIFIED UNSPECIFIED UNSPECIFIED Brooks, David J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Borghammer, Per UNSPECIFIED orcid.org/0000-0001-6391-8052 UNSPECIFIED Sommerauer, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-193268
DOI:	10.1016/j.clinph.2017.12.029
Journal or Publication Title:	Clin. Neurophysiol.
Volume:	129
Number:	3
Page Range:	S. 541 - 548
Date:	2018
Publisher:	ELSEVIER IRELAND LTD
Place of Publication:	CLARE
ISSN:	1872-8952
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EYE-MOVEMENT SLEEP; PARKINSONS-DISEASE; COERULEUS/SUBCOERULEUS COMPLEX; QUANTIFICATION; THRESHOLDS; DIAGNOSIS; SPECT; APNEA Multiple languages Clinical Neurology; Neurosciences Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/19326