Universität zu Köln

Gottschalk, Ingo, Strizek, Brigitte ORCID: 0000-0003-3625-7097, Mallmann, Michael R., Mueller, Andreas, Geipel, Annegret, Gembruch, Ulrich ORCID: 0000-0001-8284-4669, Klaritsch, Philipp ORCID: 0000-0002-7359-4853, Csapo, Bence and Berg, Christoph (2018). Outcome of Bronchopulmonary Sequestration with Massive Pleural Effusion after Intrafetal Vascular Laser Ablation. Fetal Diagn. Ther., 44 (2). S. 149 - 156. BASEL: KARGER. ISSN 1421-9964

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Abstract

Objective: To assess the outcome of 12 fetuses with bronchopulmonary sequestration (BPS) and massive pleural effusion after intrafetal vascular laser ablation (VLA). Methods: All fetuses with BPS and massive pleural effusion that were treated with intrafetal VLA during a 5-year period (2012-2016) were reviewed for safety, intrauterine course, and postnatal outcome. Results: In the study period, 12 fetuses with BPS were treated with VLA. In 7 (58.3%) fetuses, complete cessation of blood flow was achieved after the first VLA, while in 5 (41.7%) fetuses, residual perfusion of the feeding vessel was demonstrated at follow-up. A second intervention was successful in 4 of 5 (80%) fetuses. Overall, in 11 of 12 (91.7%) fetuses, complete coagulation of the feeding vessel could be achieved, followed by a reduction in size or complete resolution of the BPS. All 11 fetuses with successful prenatal intervention were live-born at a median gestational age of 39(+1) (range, 37(+5)-41(+2)) weeks. Postnatally, 2 (18.2%) of the 11 newborns underwent sequestrectomy, as well as the preterm newborn on which a second fetal intervention was not feasible. Conclusion: VLA is an effective and safe treatment of BPS that appears to be of benefit in improving prognosis and decreasing the need for postnatal sequestrectomy. (C) 2017 S. Karger AG, Basel

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Gottschalk, Ingo UNSPECIFIED UNSPECIFIED UNSPECIFIED Strizek, Brigitte UNSPECIFIED orcid.org/0000-0003-3625-7097 UNSPECIFIED Mallmann, Michael R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Mueller, Andreas UNSPECIFIED UNSPECIFIED UNSPECIFIED Geipel, Annegret UNSPECIFIED UNSPECIFIED UNSPECIFIED Gembruch, Ulrich UNSPECIFIED orcid.org/0000-0001-8284-4669 UNSPECIFIED Klaritsch, Philipp UNSPECIFIED orcid.org/0000-0002-7359-4853 UNSPECIFIED Csapo, Bence UNSPECIFIED UNSPECIFIED UNSPECIFIED Berg, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-202155
DOI:	10.1159/000479793
Journal or Publication Title:	Fetal Diagn. Ther.
Volume:	44
Number:	2
Page Range:	S. 149 - 156
Date:	2018
Publisher:	KARGER
Place of Publication:	BASEL
ISSN:	1421-9964
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EXTRALOBAR PULMONARY SEQUESTRATION; FETAL LUNG LESIONS; CYSTIC ADENOMATOID MALFORMATION; HYDROPS; ULTRASOUND; HYDROTHORAX; MANAGEMENT; DRAINAGE; SURGERY Multiple languages Obstetrics & Gynecology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/20215