Universität zu Köln

Lier, Heiko ORCID: 0000-0001-7374-4324, von Heymann, Christian, Korte, Wolfgang and Schlembach, Dietmar (2018). Peripartum Haemorrhage: Haemostatic Aspects of the New German PPH Guideline. Transfus. Med. Hemother., 45 (2). S. 127 - 136. BASEL: KARGER. ISSN 1660-3818

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Abstract

remains one of the main causes of maternal mortality world-wide. The German, Austrian and Swiss Societies of Gynaecology and Obstetrics have updated the current guidelines for the treatment of peripartum haemorrhage together with the German Society of Anaesthesiology and Intensive Care Medicine and the Society of Thrombosis and Haemostasis Research. The recommendations have been the result of a thorough review of the available scientific literature and a consensus process involving all members of the guideline group. A key element of the anaesthesiological and haemostatic management is the development of a multidisciplinary standard operating procedure combining surgical as well as medical and haemostatic treatments depending on the severity of bleeding. The guideline underscores the value of clinical and laboratory diagnostics of peripartum haemorrhage as early as possible, even pre-emptively. This allows for an early identification of causes of bleeding and a specific treatment. The guideline comprises evidence-based recommendations for the use of uterotonics, tranexamic acid and blood products such as factor concentrates, fresh frozen plasma, platelet concentrates, packed red blood cells, recombinant activated factor VII and desmopressin. In addition, recommendations for blood conservation strategies involving the use of cell salvage, permissive hypotension and transfusion triggers are given. (c) 2017 S. Karger GmbH, Freiburg

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Lier, Heiko UNSPECIFIED orcid.org/0000-0001-7374-4324 UNSPECIFIED von Heymann, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Korte, Wolfgang UNSPECIFIED UNSPECIFIED UNSPECIFIED Schlembach, Dietmar UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-203132
DOI:	10.1159/000478106
Journal or Publication Title:	Transfus. Med. Hemother.
Volume:	45
Number:	2
Page Range:	S. 127 - 136
Date:	2018
Publisher:	KARGER
Place of Publication:	BASEL
ISSN:	1660-3818
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language LEUKOCYTE DEPLETION FILTERS; ACTIVATED FACTOR-VII; POSTPARTUM HEMORRHAGE; OBSTETRIC HEMORRHAGE; CESAREAN DELIVERY; CELL SALVAGE; MASSIVE TRANSFUSION; BLEEDING DISORDERS; MANAGEMENT; PREVENTION Multiple languages Hematology; Immunology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/20313