Universität zu Köln

Schuering, A. N., Fehm, T., Behringer, K., Goeckenjan, M., Wimberger, P., Henes, M., Henes, J., Fey, M. F. and von Wolff, M. (2018). Practical recommendations for fertility preservation in women by the FertiPROTEKT network. Part I: Indications for fertility preservation. Arch. Gynecol. Obstet., 297 (1). S. 241 - 256. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0711

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Abstract

Purpose Most guidelines about fertility preservation are predominantly focused on scientific evidence, but are less practically orientated. Therefore, practically oriented recommendations are needed to support the clinician in daily practice. Methods A selective literature search was performed based on the clinical and scientific experience of the authors, focussing on the most relevant diseases and gynaecological cancers. This article (Part I) provides information on topics that are essential for the fertility preservation indication, such as disease prognosis, disease therapy and its associated risks to fertility, recommending disease-specific fertility preservation measures. Part II specifically focusses on fertility preservation techniques. Results In breast cancer patients, fertility preservation such as ovarian tissue and oocyte cryopreservation is especially recommended in low-stage cancer and in women < 35 years of age. In Hodgkin's lymphoma, the indication is mainly based on the chemotherapy regime as some therapies have very low, others very high gonadotoxicity. In borderline ovarian tumours, preservation of fertility usually is achieved through fertility sparing surgery, ovarian stimulation may also be considered. In cervical cancer, endometrial cancer, rheumatic diseases and other malignancies such as Ewing sarcoma, colorectal carcinoma, non-Hodgkin lymphoma, leukaemia etc., several other factors must be considered to enable an individual, stage-dependent decision. Conclusion The decision for or against fertility preservation depends on the prognosis, the risks to fertility and individual factors such as prospective family planning.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schuering, A. N. UNSPECIFIED UNSPECIFIED UNSPECIFIED Fehm, T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Behringer, K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Goeckenjan, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wimberger, P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Henes, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Henes, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Fey, M. F. UNSPECIFIED UNSPECIFIED UNSPECIFIED von Wolff, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-204659
DOI:	10.1007/s00404-017-4594-3
Journal or Publication Title:	Arch. Gynecol. Obstet.
Volume:	297
Number:	1
Page Range:	S. 241 - 256
Date:	2018
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1432-0711
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CRYOPRESERVED OVARIAN TISSUE; SYSTEMIC-LUPUS-ERYTHEMATOSUS; BREAST-CANCER PATIENTS; YOUNG-WOMEN; PREMENOPAUSAL WOMEN; CERVICAL-CANCER; CONSERVATIVE TREATMENT; ENDOMETRIAL CANCER; PREGNANCY OUTCOMES; NEOADJUVANT CHEMOTHERAPY Multiple languages Obstetrics & Gynecology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/20465