Universität zu Köln

Stoessel, Lisa, Schieber, Katharina, Jank, Sabine, Reber, Sandra, Grundmann, Franziska, Lueker, Christine, Vitinius, Frank, Paslakis, Georgios, Eckardt, Kai-Uwe and Erim, Yesim (2017). Up to a Third of Renal Transplant Recipients Have Deficiencies in Cognitive Functioning. Prog. Transplant., 27 (4). S. 329 - 339. THOUSAND OAKS: SAGE PUBLICATIONS INC. ISSN 2164-6708

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Abstract

Introduction: Kidney transplantation is beneficial in improving cognitive abilities in patients with chronic kidney disease; however, there is still uncertainty concerning which cognitive domains benefit and to what extent. Aim: In the present study, cognitive functioning of renal transplant recipients was compared to normative data. Sociodemographic and clinical parameters that were associated with low cognitive performance were identified. Design: A total of 109 renal transplant recipients (63% men) participated in the study, with a mean age of 51.8 (standard deviation [SD] = 14.2) years. The cognitive test battery consisted of measurements assessing memory, attention, executive function, reproductive, and deductive ability. Results: In all tests, participants showed mean scores ranging within 1 SD of the population means. However, except for tests measuring memory, the percentage of participants scoring more than 1 SD below normed means was higher than expected in a normal distribution of performance. In certain tests, up to a third of the participants scored below average. Participants with continuous low performance (11%) showed higher age, poorer education, a longer time since transplantation, higher serum levels of urea and creatinine, and were more likely to have a deceased donor allograft. Discussion: Altough cognitive performance in renal transplant recipients matches normative data and confirms former findings, the amount of patients scoring more than 1 SD below average suggests that there are a considerable number of patients whose cognitive performance in certain domains lies below those of the general population. The identified sociodemographic and biochemical factors might be helpful to identify renal transplant recipients at risk.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Stoessel, Lisa UNSPECIFIED UNSPECIFIED UNSPECIFIED Schieber, Katharina UNSPECIFIED UNSPECIFIED UNSPECIFIED Jank, Sabine UNSPECIFIED UNSPECIFIED UNSPECIFIED Reber, Sandra UNSPECIFIED UNSPECIFIED UNSPECIFIED Grundmann, Franziska UNSPECIFIED UNSPECIFIED UNSPECIFIED Lueker, Christine UNSPECIFIED UNSPECIFIED UNSPECIFIED Vitinius, Frank UNSPECIFIED UNSPECIFIED UNSPECIFIED Paslakis, Georgios UNSPECIFIED UNSPECIFIED UNSPECIFIED Eckardt, Kai-Uwe UNSPECIFIED UNSPECIFIED UNSPECIFIED Erim, Yesim UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-210646
DOI:	10.1177/1526924817731883
Journal or Publication Title:	Prog. Transplant.
Volume:	27
Number:	4
Page Range:	S. 329 - 339
Date:	2017
Publisher:	SAGE PUBLICATIONS INC
Place of Publication:	THOUSAND OAKS
ISSN:	2164-6708
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CHRONIC KIDNEY-DISEASE; PROGRESSIVE MATRICES; NORMATIVE DATA; CONSEQUENCES; HEMODIALYSIS; PERFORMANCE; IMPACT Multiple languages Surgery; Transplantation Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/21064