Universität zu Köln

Luetkens, Julian A., Schlesinger-Irsch, Ulrike, Kuetting, Daniel L., Dabir, Darius, Homsi, Rami, Doerner, Jonas, Schmeel, Frederic C., Fimmers, Rolf, Sprinkart, Alois M., Naehle, Claas P., Schild, Hans H. and Thomas, Daniel (2017). Feature-tracking myocardial strain analysis in acute myocarditis: diagnostic value and association with myocardial oedema. Eur. Radiol., 27 (11). S. 4661 - 4672. NEW YORK: SPRINGER. ISSN 1432-1084

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Abstract

Objectives To investigate the diagnostic value of cardiac magnetic resonance (CMR) feature-tracking (FT) myocardial strain analysis in patients with suspected acute myocarditis and its association with myocardial oedema. Methods Forty-eight patients with suspected acute myocarditis and 35 control subjects underwent CMR. FT CMR analysis of systolic longitudinal (LS), circumferential (CS) and radial strain (RS) was performed. Additionally, the protocol allowed for the assessment of T1 and T2 relaxation times. Results When compared with healthy controls, myocarditis patients demonstrated reduced LS, CS and RS values (LS: -19.5 +/- 4.4% vs. -23.6 +/- 3.1%, CS: -23.0 +/- 5.8% vs. -27.4 +/- 3.4%, RS: 28.9 +/- 8.5% vs. 32.4 +/- 7.4%; P < 0.05, respectively). LS (T1: r = 0.462, P < 0.001; T2: r = 0.436, P < 0.001) and CS (T1: r = 0.429, P < 0.001; T2: r = 0.467, P < 0.001) showed the strongest correlations with T1 and T2 relaxations times. Area under the curve of LS (0.79) was higher compared with those of CS (0.75; P = 0.478) and RS (0.62; P = 0.008). Conclusions FT CMR myocardial strain analysis might serve as a new tool for assessment of myocardial dysfunction in the diagnostic work-up of patients suspected of having acute myocarditis. Especially, LS and CS show a sufficient diagnostic performance and were most closely correlated with CMR parameters of myocardial oedema.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Luetkens, Julian A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schlesinger-Irsch, Ulrike UNSPECIFIED UNSPECIFIED UNSPECIFIED Kuetting, Daniel L. UNSPECIFIED UNSPECIFIED UNSPECIFIED Dabir, Darius UNSPECIFIED UNSPECIFIED UNSPECIFIED Homsi, Rami UNSPECIFIED UNSPECIFIED UNSPECIFIED Doerner, Jonas UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmeel, Frederic C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Fimmers, Rolf UNSPECIFIED UNSPECIFIED UNSPECIFIED Sprinkart, Alois M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Naehle, Claas P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schild, Hans H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Thomas, Daniel UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-212774
DOI:	10.1007/s00330-017-4854-4
Journal or Publication Title:	Eur. Radiol.
Volume:	27
Number:	11
Page Range:	S. 4661 - 4672
Date:	2017
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1432-1084
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CARDIOVASCULAR MAGNETIC-RESONANCE; INCREMENTAL VALUE; DEFORMATION; ECHOCARDIOGRAPHY; CARDIOLOGY; STATEMENT Multiple languages Radiology, Nuclear Medicine & Medical Imaging Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/21277