Universität zu Köln

Koppen, Ilan J. N., Broekaert, Ilse J., Wilschanski, Michael, Papadopoulou, Alexandra, Ribes-Koninckx, Carmen, Thapar, Nikhil, Gottrand, Frederic, Orel, Rok, Lionetti, Paolo and Benninga, Marc A. (2017). Role of Polyethylene Glycol in the Treatment of Functional Constipation in Children. J. Pediatr. Gastroenterol. Nutr., 65 (4). S. 361 - 364. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1536-4801

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Abstract

According to international guidelines, polyethylene glycol (PEG) is the laxative of first choice in the treatment of functional constipation in children, both for disimpaction and for maintenance treatment. PEG acts as an osmotic laxative and its efficacy is dose dependent. PEG is highly effective, has a good safety profile, and is well tolerated by children. Only minor adverse events have been reported. Overall the use of PEG in children has been reported to be safe, although in patients predisposed to water and electrolyte imbalances monitoring of serum electrolytes should be considered.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Koppen, Ilan J. N. UNSPECIFIED UNSPECIFIED UNSPECIFIED Broekaert, Ilse J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wilschanski, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Papadopoulou, Alexandra UNSPECIFIED UNSPECIFIED UNSPECIFIED Ribes-Koninckx, Carmen UNSPECIFIED UNSPECIFIED UNSPECIFIED Thapar, Nikhil UNSPECIFIED UNSPECIFIED UNSPECIFIED Gottrand, Frederic UNSPECIFIED UNSPECIFIED UNSPECIFIED Orel, Rok UNSPECIFIED UNSPECIFIED UNSPECIFIED Lionetti, Paolo UNSPECIFIED UNSPECIFIED UNSPECIFIED Benninga, Marc A. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-216240
DOI:	10.1097/MPG.0000000000001704
Journal or Publication Title:	J. Pediatr. Gastroenterol. Nutr.
Volume:	65
Number:	4
Page Range:	S. 361 - 364
Date:	2017
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1536-4801
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CHILDHOOD CONSTIPATION; CONTROLLED-TRIAL; DOUBLE-BLIND; PEG 4000; ELECTROLYTES; SAFETY; MULTICENTER; EFFICACY; THERAPY Multiple languages Gastroenterology & Hepatology; Nutrition & Dietetics; Pediatrics Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/21624