Universität zu Köln

Roehrig, Gabriele, Ruecker, Ymkje, Becker, Ingrid ORCID: 0000-0001-5829-3553, Schulz, Ralf-Joachim, Lenzen-Grossimlinghaus, Romana, Willschrei, Peter, Gebauer, Sybille, Modreker, Mirja, Jaeger, Martin and Wirth, Rainer ORCID: 0000-0002-7265-0163 (2017). Association of anemia with functional and nutritional status in the German multicenter study GeriAnaemie2013. Z. Gerontol. Geriatr., 50 (6). S. 532 - 538. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1435-1269

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Abstract

Objectives. Anemia and malnutrition are risk factors for frailty in older people but data from multicenter studies among German geriatric inpatients are lacking. This analysis evaluated data from the multicenter study GerAnaemie2013 commissioned by the German Geriatric Society. Patients and methods. The study involved an analysis of the 579 geriatric inpatients recruited in the context of the German multicenter study GeriAnaemie2013. Study parameters: Barthel index (BI), handgrip strength, nutritional data (e.g. loss of appetite, loss of weight and decreased food intake). Inclusion criteria: in-patient age >= 70 years, exclusion criteria: current cancer disease or cancer-associated treatment. Anemia was defined according to the World Health Organization (WHO) criteria. Results. The mean age of patients was 81.9 years, overall prevalence of anemia 55.1 %, mean hemoglobin (Hb) level 11.9 g/dl, average BI 50.8 points and 30.3 % of all patients were at risk of malnutrition. While univariate analysis revealed a significantly lower BI in anemic patients, this association was no longer seen in multivariate analysis. Regression analysis revealed that a drug intake of > 5 drugs/day doubles the chance of suffering from anemia with an adjusted odds ratio (OR) of 2.17 (confidence interval (CI) 1.28-3.68, p = 0.004) as well as a serum albumin level below 3.5 g/dl with an adjusted OR of 2.11 (range 1.40-3.19, p < 0.001). Conclusion. Polymedication and low serum albumin were independent risk factors for anemia in geriatric patients, probably reflecting disease severity.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Roehrig, Gabriele UNSPECIFIED UNSPECIFIED UNSPECIFIED Ruecker, Ymkje UNSPECIFIED UNSPECIFIED UNSPECIFIED Becker, Ingrid UNSPECIFIED orcid.org/0000-0001-5829-3553 UNSPECIFIED Schulz, Ralf-Joachim UNSPECIFIED UNSPECIFIED UNSPECIFIED Lenzen-Grossimlinghaus, Romana UNSPECIFIED UNSPECIFIED UNSPECIFIED Willschrei, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Gebauer, Sybille UNSPECIFIED UNSPECIFIED UNSPECIFIED Modreker, Mirja UNSPECIFIED UNSPECIFIED UNSPECIFIED Jaeger, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Wirth, Rainer UNSPECIFIED orcid.org/0000-0002-7265-0163 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-223094
DOI:	10.1007/s00391-016-1092-3
Journal or Publication Title:	Z. Gerontol. Geriatr.
Volume:	50
Number:	6
Page Range:	S. 532 - 538
Date:	2017
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1435-1269
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SERUM-ALBUMIN; ELDERLY-PEOPLE; OLDER-ADULTS; PREVALENCE; MORTALITY; MALNUTRITION; GERIATRICS; FRAILTY; HEALTH; IMPACT Multiple languages Geriatrics & Gerontology; Gerontology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/22309