Eichler, C. and Warm, M. (2017). Neoadjuvant or not? Aspects of treatment planning after 20 years of neoadjuvant therapy. Gynakologe, 50 (7). S. 488 - 498. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-0393
Full text not available from this repository.Abstract
Approximately 20 years of structured breast cancer (BC) data analysis on neoadjuvant chemotherapy with regards to disease-free survival (DFS) und overall survival (OS) is available today. A plethora of trials showed the advantage of neoadjuvant vs. adjuvant therapy over the course of time. Therefore, whenever necessary, the administration of chemotherapy preoperatively has become the gold standard in breast cancer therapy today. Despite a multitude of novel drugs and targeted therapy, basic cytotoxic treatment is still mandatory for HR+/HER2- BC (high risk, luminal B), HR+ and HR-/HER2+ BC and triple-negative BC (TNBC). This article will summarize the current standards of neoadjuvant treatment and discuss available decision-making tools and treatment options for neoadjuvant chemotherapy today.
Item Type: | Journal Article | ||||||||||||
Creators: |
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URN: | urn:nbn:de:hbz:38-225445 | ||||||||||||
DOI: | 10.1007/s00129-017-4091-6 | ||||||||||||
Journal or Publication Title: | Gynakologe | ||||||||||||
Volume: | 50 | ||||||||||||
Number: | 7 | ||||||||||||
Page Range: | S. 488 - 498 | ||||||||||||
Date: | 2017 | ||||||||||||
Publisher: | SPRINGER HEIDELBERG | ||||||||||||
Place of Publication: | HEIDELBERG | ||||||||||||
ISSN: | 1433-0393 | ||||||||||||
Language: | German | ||||||||||||
Faculty: | Unspecified | ||||||||||||
Divisions: | Unspecified | ||||||||||||
Subjects: | no entry | ||||||||||||
Uncontrolled Keywords: |
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Refereed: | Yes | ||||||||||||
URI: | http://kups.ub.uni-koeln.de/id/eprint/22544 |
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