Universität zu Köln

Hedderich, Dennis M., Hasenberg, Till ORCID: 0000-0003-2681-8006, Haneder, Stefan, Schoenberg, Stefan O., Kucukoglu, Ozlem ORCID: 0000-0002-4217-9075, Canbay, Ali ORCID: 0000-0001-6069-7899 and Otto, Mirko (2017). Effects of Bariatric Surgery on Non-alcoholic Fatty Liver Disease: Magnetic Resonance Imaging Is an Effective, Non-invasive Method to Evaluate Changes in the Liver Fat Fraction. Obes. Surg., 27 (7). S. 1755 - 1763. NEW YORK: SPRINGER. ISSN 1708-0428

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Abstract

Non-alcoholic fatty liver disease (NAFLD) is considered the most common liver disease worldwide and is highly associated with obesity. The prevalences of both conditions have markedly increased in the Western civilization. Bariatric surgery is the most effective treatment for morbid obesity and its comorbidities such as NAFLD. Measure postoperative liver fat fraction (LFF) in bariatric patients by using in-opposed-phase MRI, a widely available clinical tool validated for the quantification of liver fat Retrospective analyses of participants, who underwent laparoscopic Roux-Y-gastric-bypass (17) or laparoscopic sleeve gastrectomy (2) were performed using magnetic resonance imaging (MRI), bioelectrical impedance analysis (BIA), and anthropometric measurements 1 day before surgery, as well as 6, 12, and 24 weeks after surgery, LFF was calculated from fat-only and water-only MR images. Six months after surgery, a significant decrease of LFF and liver volume has been observed along with weight loss, decreased waist circumference, and parameters obtained by body fat measured by BIA. LFF significantly correlated with liver volume in the postoperative course. MRI including in-opposed-phase imaging of the liver can detect the quantitative decrease of fatty infiltration within the liver after bariatric surgery and thus could be a valuable tool to monitor NAFLD/NASH postoperatively.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Hedderich, Dennis M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hasenberg, Till UNSPECIFIED orcid.org/0000-0003-2681-8006 UNSPECIFIED Haneder, Stefan UNSPECIFIED UNSPECIFIED UNSPECIFIED Schoenberg, Stefan O. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kucukoglu, Ozlem UNSPECIFIED orcid.org/0000-0002-4217-9075 UNSPECIFIED Canbay, Ali UNSPECIFIED orcid.org/0000-0001-6069-7899 UNSPECIFIED Otto, Mirko UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-226038
DOI:	10.1007/s11695-016-2531-3
Journal or Publication Title:	Obes. Surg.
Volume:	27
Number:	7
Page Range:	S. 1755 - 1763
Date:	2017
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1708-0428
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MORBIDLY OBESE-PATIENTS; HEPATIC STEATOSIS; GASTRIC BYPASS; STEATOHEPATITIS; SPECTROSCOPY; PREVALENCE; QUANTIFICATION; EPIDEMIOLOGY; METAANALYSIS; PREDICTORS Multiple languages Surgery Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/22603