Universität zu Köln

Schaub, Friederike, Enders, Philip ORCID: 0000-0002-9527-4957, Snijders, Katharina, Schrittenlocher, Silvia ORCID: 0000-0001-6090-6777, Siebelmann, Sebastian, Heindl, Ludwig M., Bachmann, Bjoern O. and Cursiefen, Claus (2017). One-year outcome after Descemet membrane endothelial keratoplasty (DMEK) comparing sulfur hexafluoride (SF6) 20% versus 100% air for anterior chamber tamponade. Br. J. Ophthalmol., 101 (7). S. 902 - 909. LONDON: BMJ PUBLISHING GROUP. ISSN 1468-2079

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Abstract

Purpose To investigate 1-year clinical outcome and complication rates following Descemet membrane endothelial keratoplasty (DMEK) with sulfur hexafluoride 20% (SF(6)20%) anterior chamber tamponade compared with conventionally used 100% air for primary graft attachment during DMEK surgery. Methods Records of 1112 consecutive DMEKs were reviewed retrospectively and grouped by anterior chamber tamponade used during DMEK surgery (SF(6)20% vs 100% air). Outcome measures included intraocular pressure (IOP), best spectacle-corrected visual acuity (BSCVA), endothelial cell density (ECD) and central corneal thickness (CCT) at 1, 3, 6 and 12 months after DMEK surgery. Complication rates were assessed, including intraoperative and postoperative complications, and graft detachment rate requiring rebubbling. Results A total of 854 cases were included in this study. In 105 cases (12.3%), DMEK was performed with SF(6)20%, and in 749 cases (87.7%) 100% air was used for anterior chamber tamponade. Outcome results for IOP, BSCVA, ECD and CCT at all follow-up time points were comparable for both anterior chamber tamponade groups without statistical significant differences (p=0.05), but graft detachment rate requiring rebubbling was significantly lower in the SF(6)20% group (p<0.001). Conclusion Whereas SF(6)20% anterior chamber tamponade does not seem to negatively affect the clinical outcome of DMEK surgery within the first postoperative year, use of SF(6)20% significantly reduces the rate of rebubblings.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schaub, Friederike UNSPECIFIED UNSPECIFIED UNSPECIFIED Enders, Philip UNSPECIFIED orcid.org/0000-0002-9527-4957 UNSPECIFIED Snijders, Katharina UNSPECIFIED UNSPECIFIED UNSPECIFIED Schrittenlocher, Silvia UNSPECIFIED orcid.org/0000-0001-6090-6777 UNSPECIFIED Siebelmann, Sebastian UNSPECIFIED UNSPECIFIED UNSPECIFIED Heindl, Ludwig M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bachmann, Bjoern O. UNSPECIFIED UNSPECIFIED UNSPECIFIED Cursiefen, Claus UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-226248
DOI:	10.1136/bjophthalmol-2016-309653
Journal or Publication Title:	Br. J. Ophthalmol.
Volume:	101
Number:	7
Page Range:	S. 902 - 909
Date:	2017
Publisher:	BMJ PUBLISHING GROUP
Place of Publication:	LONDON
ISSN:	1468-2079
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language POSTERIOR LAMELLAR KERATOPLASTY; GRAFT DETACHMENT; LEARNING-CURVE; PERFLUOROPROPANE; GASES Multiple languages Ophthalmology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/22624