Universität zu Köln

van der Steen, Y., Gimpel-Drees, J., Lataster, T., Viechtbauer, W., Simons, C. J. P., Lardinois, M., Michel, T. M., Janssen, B., Bechdolf, A., Wagner, M. and Myin-Germeys, I. (2017). Clinical high risk for psychosis: the association between momentary stress, affective and psychotic symptoms. Acta Psychiatr. Scand., 136 (1). S. 63 - 74. HOBOKEN: WILEY. ISSN 1600-0447

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Abstract

Objective: The aim of this study was to assess associations between momentary stress and both affective and psychotic symptoms in everyday life of individuals at clinical high risk (CHR), compared to chronic psychotic patients and healthy controls, in search for evidence of early stress sensitization. It also assessed whether psychotic experiences were experienced as stressful. Method: The experience sampling method was used to measure affective and psychotic reactivity to everyday stressful activities, events and social situations in 22 CHR patients, 24 patients with a psychotic disorder and 26 healthy controls. Results: Multilevel models showed significantly larger associations between negative affect (NA) and activity-related stress for CHR patients than for psychotic patients (P = 0.008) and for CHR compared to controls (P < 0.001). Similarly, the association between activity-related stress and psychotic symptoms was larger in CHR than in patients (P = 0.02). Finally, the association between NA and symptoms (P < 0.001) was larger in CHR than in patients. Conclusion: Stress sensitization seems to play a role particularly in the early phase of psychosis development as results suggest that CHR patients are more sensitive to daily life stressors than psychotic patients. In this early phase, psychotic experiences also contributed to the experience of stress.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code van der Steen, Y. UNSPECIFIED UNSPECIFIED UNSPECIFIED Gimpel-Drees, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Lataster, T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Viechtbauer, W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Simons, C. J. P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Lardinois, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Michel, T. M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Janssen, B. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bechdolf, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wagner, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Myin-Germeys, I. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-227017
DOI:	10.1111/acps.12714
Journal or Publication Title:	Acta Psychiatr. Scand.
Volume:	136
Number:	1
Page Range:	S. 63 - 74
Date:	2017
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1600-0447
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ULTRA-HIGH-RISK; DAILY-LIFE STRESS; CHILDHOOD TRAUMA; COMPREHENSIVE ASSESSMENT; EMOTIONAL REACTIVITY; NEGATIVE SYMPTOMS; YOUNG-PEOPLE; SCHIZOPHRENIA; INDIVIDUALS; EVENTS Multiple languages Psychiatry Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/22701