Universität zu Köln

Macherey, Sascha, Mallmann, Peter, Malter, Wolfram, Doerr, Fabian, Heldwein, Matthias, Wahlers, Thorsten and Hekmat, Khosro (2017). Lung Metastasectomy for Pulmonary Metastatic Breast Carcinoma. Geburtshilfe Frauenheilkd., 77 (6). S. 645 - 651. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1438-8804

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Abstract

Breast carcinoma with pulmonary metastasis can be treated locally or systemically. Following primary tumour resection patients with isolated, completely resectable pulmonary nodules and definite functional operability can be offered lung metastasis resection. Following metastasectomy a median survival of 32 to 96.6 months can be achieved with corresponding five-year survival rates between 30.8 and 54.4%. The procedure is associated with a mortality rate of 0 to 3%. The most important independent prognostic factor for long-term survival is complete resection of all lung lesions. The configuration and pattern of metastasis as well as disease-free interval, hormone and HER2/neu receptor status also appear to influence prognosis, but are of lesser importance. Intrapulmonary recurrence of metastases may, after careful selection on a case-by-case basis, also be treated operatively. In some cases this is associated with a favourable long-term prognosis. Pulmonary metastasectomy should be the treatment of choice for selected patients with metastatic breast carcinoma.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Macherey, Sascha UNSPECIFIED UNSPECIFIED UNSPECIFIED Mallmann, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Malter, Wolfram UNSPECIFIED UNSPECIFIED UNSPECIFIED Doerr, Fabian UNSPECIFIED UNSPECIFIED UNSPECIFIED Heldwein, Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED Wahlers, Thorsten UNSPECIFIED UNSPECIFIED UNSPECIFIED Hekmat, Khosro UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-228600
DOI:	10.1055/s-0043-108252
Journal or Publication Title:	Geburtshilfe Frauenheilkd.
Volume:	77
Number:	6
Page Range:	S. 645 - 651
Date:	2017
Publisher:	GEORG THIEME VERLAG KG
Place of Publication:	STUTTGART
ISSN:	1438-8804
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CANCER PATIENTS; RESECTION; SURGERY; SURVIVAL Multiple languages Obstetrics & Gynecology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/22860