Universität zu Köln

Bachmann, Bjoen O. and Schrader, Stefan (2017). Biomaterials or Donor Tissue - What is the Future of Tissue Engenieering for Cornea Reconstruction? Klinische Monatsblat. Augenheilkunde, 234 (6). S. 758 - 763. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1439-3999

Full text not available from this repository.

Abstract

For the replacement of corneal tissue, corneal grafts or amniotic membrane are still used as a standard material. Since this is biological tissue, there is only a limited standardization regarding preparation, tissue properties and behaviour after transplantation. In addition, there is a risk of disease transmission, and the availability of both human corneas and amniotic membrane is insufficient in many regions of the world, which is why alternative biomaterials have been explored for many years now. Among the natural biomaterials, materials based on collagen or keratin provide characteristics that make them good candidates for corneal tissue replacement. However, there are still many unsolved problems, particularly regarding the degradation after implantation and the seam strength of the materials. Initial clinical studies with different biomaterials based on collagen prove their good biocompatibility to integrate and their low immunogenicity. Currently, there is no biomaterial that meets the requirements in every situation. It can be assumed that different biomaterials will be available in the future, which, depending on the underlying corneal disease, will fulfill different functions and thus make a patient- and disease-specific care possible.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Bachmann, Bjoen O. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schrader, Stefan UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-229151
DOI:	10.1055/s-0043-109024
Journal or Publication Title:	Klinische Monatsblat. Augenheilkunde
Volume:	234
Number:	6
Page Range:	S. 758 - 763
Date:	2017
Publisher:	GEORG THIEME VERLAG KG
Place of Publication:	STUTTGART
ISSN:	1439-3999
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language OCULAR SURFACE RECONSTRUCTION; PLASTIC COMPRESSED COLLAGEN; IN-VITRO; ARTIFICIAL CORNEA; KERATIN FILMS; CELL-CULTURE; IMPLANTATION; BIOCOMPATIBILITY; REGENERATION; SUBSTITUTE Multiple languages Ophthalmology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/22915