Rowe, Steven P., Gorin, Michael A., Fragomeni, Roberto A. Salas, Drzezga, Alexander and Pomper, Martin G. (2017). Clinical Experience with F-18-Labeled Small Molecule Inhibitors of Prostate- Specific Membrane Antigen. PET Clin., 12 (2). S. 235 - 242. SAN DIEGO: ELSEVIER INC. ISSN 1559-7814

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Abstract

Prostate cancer (PCa) is the most common noncutaneous malignancy diagnosed in men. Despite the large number of men who will suffer from PCa at some point during their lives, conventional imaging modalities for this important disease (contrast-enhanced computed tomography, bone scan, and MR imaging) have provided only marginal to moderate success in appropriately guiding patient management in certain clinical contexts. In this review, the authors discuss radiofluorinated small molecule radiotracers that have been developed to bind to the transmembrane glycoprotein prostate-specific membrane antigen, a target that is nearly universally overexpressed on PCa epithelial cells.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Rowe, Steven P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gorin, Michael A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fragomeni, Roberto A. SalasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Drzezga, AlexanderUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pomper, Martin G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-235398
DOI: 10.1016/j.cpet.2016.12.006
Journal or Publication Title: PET Clin.
Volume: 12
Number: 2
Page Range: S. 235 - 242
Date: 2017
Publisher: ELSEVIER INC
Place of Publication: SAN DIEGO
ISSN: 1559-7814
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
POSITRON-EMISSION-TOMOGRAPHY; RENAL-CELL CARCINOMA; TUMOR-ASSOCIATED NEOVASCULATURE; F-18-DCFPYL PET/CT; CANCER; PSMA; EXPRESSION; ACID; RECURRENCE; MODELSMultiple languages
Radiology, Nuclear Medicine & Medical ImagingMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/23539

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