Universität zu Köln

Linden, Katharina, Ladage, Dennis ORCID: 0000-0002-4512-0917, Dewald, Oliver, Gatzweiler, Eva ORCID: 0000-0002-2015-6673, Pieper, Andrea, Seehase, Matthias, Duerr, Georg Daniel, Breuer, Johannes and Herberg, Ulrike (2017). Comparison of stroke volumes assessed by three-dimensional echocardiography and transpulmonary thermodilution in a pediatric animal model. J. Clin. Monitor. Comp., 31 (2). S. 353 - 361. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1573-2614

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Abstract

To compare stroke volumes (SV) in small hearts assessed by real-time three-dimensional echocardiography (3DE) with SV measured by transpulmonary thermodilution (TPTD) and continuous pulse contour analysis (PC) under various hemodynamic conditions. In thirteen anesthetized piglets (range 3.6-7.1 kg) SV were measured by 3DE, TPTD and PC at baseline and during phenylephrine and esmolol administration. 3DE and TPTD measurements were done successively while SV calculated by PC was documented at the time of 3DE. 3DE and TPTD showed a good correlation (r(2) = 0.74) and a bias of -1.3 ml (limits of agreement -4.1 to 1.5 ml). While TPTD measured higher SV than 3DE, both methods tracked SV changes with a concordance rate of 91 %. PC and 3DE showed a lower correlation coefficient of r(2) = 0.57 and a bias of -2.1 ml (limits of agreement -5.9 to 1.8 ml). Inter- and intra-observer variability of SV measured by 3DE was good with a mean bias < 5 %. SV3DE showed a small variance and tracked acute small changes in SV in acceptable concordance with TPTD. PC measured SV with a higher variance and mean difference compared to 3DE. In an experimental setting 3DE has the possibility to offer non-invasive assessments of ventricular volumes volume changes. To determine whether 3DE could be used for SV assessment in a clinical routine our results need confirmation in a clinical setting.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Linden, Katharina UNSPECIFIED UNSPECIFIED UNSPECIFIED Ladage, Dennis UNSPECIFIED orcid.org/0000-0002-4512-0917 UNSPECIFIED Dewald, Oliver UNSPECIFIED UNSPECIFIED UNSPECIFIED Gatzweiler, Eva UNSPECIFIED orcid.org/0000-0002-2015-6673 UNSPECIFIED Pieper, Andrea UNSPECIFIED UNSPECIFIED UNSPECIFIED Seehase, Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED Duerr, Georg Daniel UNSPECIFIED UNSPECIFIED UNSPECIFIED Breuer, Johannes UNSPECIFIED UNSPECIFIED UNSPECIFIED Herberg, Ulrike UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-235605
DOI:	10.1007/s10877-016-9843-7
Journal or Publication Title:	J. Clin. Monitor. Comp.
Volume:	31
Number:	2
Page Range:	S. 353 - 361
Date:	2017
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1573-2614
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CARDIAC-OUTPUT MEASUREMENT; CONGENITAL HEART-DISEASE; LEFT-VENTRICULAR INDEXES; MAGNETIC-RESONANCE; VENTILATED CHILDREN; EJECTION FRACTION; DIRECT FICK; VALIDATION; INFANTS; FEASIBILITY Multiple languages Anesthesiology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/23560