Universität zu Köln

Schierholz, Irina, Finke, Mareike, Kral, Andrej ORCID: 0000-0002-7762-4642, Buechner, Andreas, Rach, Stefan ORCID: 0000-0001-5241-0253, Lenarz, Thomas, Dengler, Reinhard and Sandmann, Pascale (2017). Auditory and Audio-Visual Processing in Patients with Cochlear, Auditory Brainstem, and Auditory Midbrain Implants: An EEG Study. Hum. Brain Mapp., 38 (4). S. 2206 - 2226. HOBOKEN: WILEY-BLACKWELL. ISSN 1097-0193

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Abstract

There is substantial variability in speech recognition ability across patients with cochlear implants (CIs), auditory brainstem implants (ABIs), and auditory midbrain implants (AMIs). To better understand how this variability is related to central processing differences, the current electroencephalography (EEG) study compared hearing abilities and auditory-cortex activation in patients with electrical stimulation at different sites of the auditory pathway. Three different groups of patients with auditory implants (Hannover Medical School; ABI: n = 6, CI: n = 6; AMI: n = 2) performed a speeded response task and a speech recognition test with auditory, visual, and audio-visual stimuli. Behavioral performance and cortical processing of auditory and audio-visual stimuli were compared between groups. ABI and AMI patients showed prolonged response times on auditory and audio-visual stimuli compared with NH listeners and CI patients. This was confirmed by prolonged N1 latencies and reduced N1 amplitudes in ABI and AMI patients. However, patients with central auditory implants showed a remarkable gain in performance when visual and auditory input was combined, in both speech and non-speech conditions, which was reflected by a strong visual modulation of auditory-cortex activation in these individuals. In sum, the results suggest that the behavioral improvement for audio-visual conditions in central auditory implant patients is based on enhanced audio-visual interactions in the auditory cortex. Their findings may provide important implications for the optimization of electrical stimulation and rehabilitation strategies in patients with central auditory prostheses. (C) 2017 Wiley Periodicals, Inc.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schierholz, Irina UNSPECIFIED UNSPECIFIED UNSPECIFIED Finke, Mareike UNSPECIFIED UNSPECIFIED UNSPECIFIED Kral, Andrej UNSPECIFIED orcid.org/0000-0002-7762-4642 UNSPECIFIED Buechner, Andreas UNSPECIFIED UNSPECIFIED UNSPECIFIED Rach, Stefan UNSPECIFIED orcid.org/0000-0001-5241-0253 UNSPECIFIED Lenarz, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Dengler, Reinhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Sandmann, Pascale UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-236181
DOI:	10.1002/hbm.23515
Journal or Publication Title:	Hum. Brain Mapp.
Volume:	38
Number:	4
Page Range:	S. 2206 - 2226
Date:	2017
Publisher:	WILEY-BLACKWELL
Place of Publication:	HOBOKEN
ISSN:	1097-0193
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language INDEPENDENT COMPONENT ANALYSIS; POSITRON-EMISSION-TOMOGRAPHY; EVENT-RELATED POTENTIALS; MULTISENSORY INTEGRATION; NEUROFIBROMATOSIS TYPE-2; INFERIOR COLLICULUS; EVOKED-POTENTIALS; SPEECH-PERCEPTION; ASCENDING PROJECTIONS; ELECTRIC-STIMULATION Multiple languages Neurosciences; Neuroimaging; Radiology, Nuclear Medicine & Medical Imaging Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/23618