Universität zu Köln

Becker, Jan U. (2017). Current status of pediatric renal transplant pathology. Pediatr. Nephrol., 32 (3). S. 425 - 438. NEW YORK: SPRINGER. ISSN 1432-198X

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Abstract

Histopathology is still an indispensable tool for the diagnosis of kidney transplant dysfunction in adult and pediatric patients. This review presents consolidated knowledge, recent developments and future prospects on the biopsy procedure, the diagnostic work-up, classification schemes, the histopathology of rejection, including antibody-mediated forms, ABO-incompatible transplants, protocol biopsies, recurrent and de novo disease, post-transplant lymphoproliferative disorder, infectious complications and drug-induced toxicity. It is acknowledged that frequently the correct diagnosis can only be reached in consensus with clinical, serological, immunogenetical, bacteriological and virological findings. This review shall enhance the understanding of the pediatric nephrologist for the thought processes of nephropathologists with the aim to facilitate teamwork between these specialist groups for the benefit of the patient.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Becker, Jan U. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-238704
DOI:	10.1007/s00467-016-3381-x
Journal or Publication Title:	Pediatr. Nephrol.
Volume:	32
Number:	3
Page Range:	S. 425 - 438
Date:	2017
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1432-198X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language FOCAL SEGMENTAL GLOMERULOSCLEROSIS; ANTIBODY-MEDIATED REJECTION; HEMOLYTIC-UREMIC SYNDROME; DONOR-SPECIFIC ANTIBODIES; ALLOGRAFT BIOPSIES; KIDNEY-TRANSPLANTATION; PROTOCOL BIOPSIES; C4D DEPOSITION; MICROCIRCULATION INFLAMMATION; WORKING CLASSIFICATION Multiple languages Pediatrics; Urology & Nephrology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/23870