Genon, Sarah, Li, Hai, Fan, Lingzhong, Mueller, Veronika I., Cieslik, Edna C., Hoffstaedter, Felix ORCID: 0000-0001-7163-3110, Reid, Andrew T., Langner, Robert ORCID: 0000-0002-3237-001X, Grefkes, Christian ORCID: 0000-0002-1656-720X, Fox, Peter T., Moebus, Susanne, Caspers, Svenja ORCID: 0000-0001-5083-4669, Amunts, Katrin ORCID: 0000-0001-5828-0867, Jiang, Tianzi ORCID: 0000-0001-9531-291X and Eickhoff, Simon B. ORCID: 0000-0001-6363-2759 (2017). The Right Dorsal Premotor Mosaic: Organization, Functions, and Connectivity. Cereb. Cortex, 27 (3). S. 2095 - 2111. CARY: OXFORD UNIV PRESS INC. ISSN 1460-2199

Full text not available from this repository.

Abstract

The right dorsal premotor cortex (PMd) of humans has been reported to be involved in a broad range of motor and cognitive functions. We explored the basis of this behavioral heterogeneity by performing a connectivity-based parcellation using metaanalytic approach applied to PMd coactivations. We compared our connectivity-based parcellation results with parcellations obtained through resting-state functional connectivity and probabilistic diffusion tractography. Functional connectivity profiles and behavioral decoding of the resulting PMd subregions allowed characterizing their respective behavior profile. These procedures divided the right PMd into 5 distinct subregions that formed a cognitive-motor gradient along a rostro-caudal axis. In particular, we found 1) a rostral subregion functionally connected with prefrontal cortex, which likely supports high-level cognitive processes, such as working memory, 2) a central subregion showing a mixed behavioral profile and functional connectivity to parietal regions of the dorsal attention network, and 3) a caudal subregion closely integrated with the motor system. Additionally, we found 4) a dorsal subregion, preferentially related to handmovements and connected to both cognitive and motor regions, and 5) a ventral subregion, whose functional profile fits the concept of an eye movement-related field. In conclusion, right PMd may be considered as a functional mosaic formed by 5 subregions.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Genon, SarahUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Li, HaiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fan, LingzhongUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mueller, Veronika I.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cieslik, Edna C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hoffstaedter, FelixUNSPECIFIEDorcid.org/0000-0001-7163-3110UNSPECIFIED
Reid, Andrew T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Langner, RobertUNSPECIFIEDorcid.org/0000-0002-3237-001XUNSPECIFIED
Grefkes, ChristianUNSPECIFIEDorcid.org/0000-0002-1656-720XUNSPECIFIED
Fox, Peter T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Moebus, SusanneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Caspers, SvenjaUNSPECIFIEDorcid.org/0000-0001-5083-4669UNSPECIFIED
Amunts, KatrinUNSPECIFIEDorcid.org/0000-0001-5828-0867UNSPECIFIED
Jiang, TianziUNSPECIFIEDorcid.org/0000-0001-9531-291XUNSPECIFIED
Eickhoff, Simon B.UNSPECIFIEDorcid.org/0000-0001-6363-2759UNSPECIFIED
URN: urn:nbn:de:hbz:38-238832
DOI: 10.1093/cercor/bhw065
Journal or Publication Title: Cereb. Cortex
Volume: 27
Number: 3
Page Range: S. 2095 - 2111
Date: 2017
Publisher: OXFORD UNIV PRESS INC
Place of Publication: CARY
ISSN: 1460-2199
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
HUMAN BRAIN; CYTOARCHITECTONIC AREAS; PARIETAL LOBULE; WORKING-MEMORY; PRIMARY MOTOR; CORTEX; PARCELLATION; REGION; ARCHITECTURE; METAANALYSISMultiple languages
NeurosciencesMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/23883

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item