Universität zu Köln

Chong, Trevor T. -J., Apps, Matthew ORCID: 0000-0001-5793-2202, Giehl, Kathrin, Sillence, Annie, Grima, Laura L. and Husain, Masud ORCID: 0000-0002-6850-9255 (2017). Neurocomputational mechanisms underlying subjective valuation of effort costs. PLoS. Biol., 15 (2). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1545-7885

Full text not available from this repository.

Abstract

In everyday life, we have to decide whether it is worth exerting effort to obtain rewards. Effort can be experienced in different domains, with some tasks requiring significant cognitive demand and others being more physically effortful. The motivation to exert effort for reward is highly subjective and varies considerably across the different domains of behaviour. However, very little is known about the computational or neural basis of how different effort costs are subjectively weighed against rewards. Is there a common, domain-general system of brain areas that evaluates all costs and benefits? Here, we used computational modelling and functional magnetic resonance imaging (fMRI) to examine the mechanisms underlying value processing in both the cognitive and physical domains. Participants were trained on two novel tasks that parametrically varied either cognitive or physical effort. During fMRI, participants indicated their preferences between a fixed low-effort/low-reward option and a variable higher-effort/higher-reward offer for each effort domain. Critically, reward devaluation by both cognitive and physical effort was subserved by a common network of areas, including the dorsomedial and dorsolateral prefrontal cortex, the intraparietal sulcus, and the anterior insula. Activity within these domain-general areas also covaried negatively with reward and positively with effort, suggesting an integration of these parameters within these areas. Additionally, the amygdala appeared to play a unique, domain-specific role in processing the value of rewards associated with cognitive effort. These results are the first to reveal the neurocomputational mechanisms underlying subjective cost-benefit valuation across different domains of effort and provide insight into the multidimensional nature of motivation.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Chong, Trevor T. -J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Apps, Matthew UNSPECIFIED orcid.org/0000-0001-5793-2202 UNSPECIFIED Giehl, Kathrin UNSPECIFIED UNSPECIFIED UNSPECIFIED Sillence, Annie UNSPECIFIED UNSPECIFIED UNSPECIFIED Grima, Laura L. UNSPECIFIED UNSPECIFIED UNSPECIFIED Husain, Masud UNSPECIFIED orcid.org/0000-0002-6850-9255 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-241909
DOI:	10.1371/journal.pbio.1002598
Journal or Publication Title:	PLoS. Biol.
Volume:	15
Number:	2
Date:	2017
Publisher:	PUBLIC LIBRARY SCIENCE
Place of Publication:	SAN FRANCISCO
ISSN:	1545-7885
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ANTERIOR CINGULATE CORTEX; DORSOLATERAL PREFRONTAL CORTEX; DECISION-MAKING; ORBITOFRONTAL CORTEX; BASOLATERAL AMYGDALA; COGNITIVE EFFORT; PARIETAL CORTEX; PHYSICAL EFFORT; INDIVIDUAL-DIFFERENCES; NEURAL MECHANISMS Multiple languages Biochemistry & Molecular Biology; Biology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/24190