Universität zu Köln

Hajek, Andr, Brettschneider, C., Posselt, T., Lange, C., Mamone, S., Wiese, B., Weyerer, S., Werle, J., Fuchs, A., Pentzek, M., Stein, J., Luck, T., Bickel, H., Mosch, E., Heser, K., Jessen, F., Maier, W., Scherer, M., Riedel-Heller, S. G. and Konig, H. -H. (2016). Predictors of frailty in old age-results of a longitudinal study. J. Nutr. Health Aging, 20 (9). S. 952 - 958. PARIS: SPRINGER FRANCE. ISSN 1760-4788

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Abstract

To investigate time-dependent predictors of frailty in old age longitudinally. Population-based prospective cohort study. Elderly individuals were recruited via GP offices at six study centers in Germany. The course of frailty was observed over 1.5 years (follow up wave 4 and follow up wave 5). 1,602 individuals aged 80 years and older (mean age 85.4 years SD 3.2, with mean CSHA CFS 3.5 SD 1.6) at follow up wave 4. Frailty was assessed by using the Canadian Study of Health and Aging Clinical Frailty Scale (CSHA CFS), ranging from 1 (very fit) to 7 (severely frail). Fixed effects regressions revealed that frailty increased significantly with increasing age (=.2) as well as the occurrence of depression (=.5) and dementia (=.8) in the total sample. Changes in marital status and comorbidity did not affect frailty. While the effects of depression and dementia were significant in women, these effects did not achieve statistical significance in men. Our findings highlight the role of aging as well as the occurrence of dementia and depression for frailty. Specifically, in order to delay frailty in old age, developing interventional strategies to prevent depression might be a fruitful approach.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Hajek, Andr UNSPECIFIED UNSPECIFIED UNSPECIFIED Brettschneider, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Posselt, T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Lange, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Mamone, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wiese, B. UNSPECIFIED UNSPECIFIED UNSPECIFIED Weyerer, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Werle, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Fuchs, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Pentzek, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Stein, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Luck, T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bickel, H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Mosch, E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Heser, K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Jessen, F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Maier, W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Scherer, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Riedel-Heller, S. G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Konig, H. -H. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-257831
DOI:	10.1007/s12603-015-0634-5
Journal or Publication Title:	J. Nutr. Health Aging
Volume:	20
Number:	9
Page Range:	S. 952 - 958
Date:	2016
Publisher:	SPRINGER FRANCE
Place of Publication:	PARIS
ISSN:	1760-4788
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MILD COGNITIVE IMPAIRMENT; WOMENS HEALTH; INCIDENT FRAILTY; ESTABLISHED POPULATIONS; DEPRESSIVE SYMPTOMS; MEXICAN-AMERICANS; TRANSITIONS; RISK; PREVALENCE; DISABILITY Multiple languages Geriatrics & Gerontology; Nutrition & Dietetics Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/25783