Universität zu Köln

Flesch, M., Morbach, S., Erdmann, E. and Bulut, D. (2016). Wine consumption and prevention of coronary artery disease. Herz, 41 (6). S. 469 - 478. MUNICH: URBAN & VOGEL. ISSN 1615-6692

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Abstract

There is a J-shaped correlation between the amount of alcohol consumed per day and overall mortality risk and an inverse correlation between the amount of alcohol consumed per day and cardiovascular mortality. The evidence is stronger for men than for women. The correlations are independent of the type of alcoholic beverage predominantly consumed. Possible mechanisms explaining the cardioprotective, antiatherosclerotic effects of moderate alcohol consumption are inhibition of platelet aggregation, increase in serum high density lipoprotein (HDL) levels and prevention of diabetes mellitus. The two latter mechanisms can also explain a delayed progression of atherosclerosis due to alcohol consumption. The beneficial effects are counteracted by detrimental effects of alcohol on the incidence of cancer diseases, liver cirrhosis, violence and accidents; therefore, alcohol consumption in general cannot be recommended for prevention of cardiovascular diseases.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Flesch, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Morbach, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Erdmann, E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bulut, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-264356
DOI:	10.1007/s00059-016-4467-8
Journal or Publication Title:	Herz
Volume:	41
Number:	6
Page Range:	S. 469 - 478
Date:	2016
Publisher:	URBAN & VOGEL
Place of Publication:	MUNICH
ISSN:	1615-6692
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MODERATE ALCOHOL INTAKE; HIGH-DENSITY-LIPOPROTEIN; US MALE PHYSICIANS; MIDDLE-AGED MEN; HEART-DISEASE; MYOCARDIAL-INFARCTION; RED WINE; CARDIOVASCULAR-DISEASE; PLATELET-AGGREGATION; HEMOSTATIC FACTORS Multiple languages Cardiac & Cardiovascular Systems Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/26435