Kar, Siddhartha P. ORCID: 0000-0002-2314-1426, Beesley, Jonathan ORCID: 0000-0003-1942-325X, Al Olama, Ali Amin, Michailidou, Kyriaki ORCID: 0000-0001-7065-1237, Tyrer, Jonathan, Kote-Jarai, Zsofi A., Lawrenson, Kate, Lindstrom, Sara, Ramus, Susan J., Thompson, Deborah J., Kibel, Adam S., Dansonka-Mieszkowska, Agnieszka ORCID: 0000-0002-2482-6523, Michael, Agnieszka ORCID: 0000-0002-7262-6227, Dieffenbach, Aida K., Gentry-Maharaj, Aleksandra, Whittemore, Alice S., Wolk, Alicja, Monteiro, Alvaro, Peixoto, Ana ORCID: 0000-0002-1404-5897, Kierzek, Andrzej, Cox, Angela ORCID: 0000-0002-5138-1099, Rudolph, Anja, Gonzalez-Neira, Anna ORCID: 0000-0002-5421-2020, Wu, Anna H., Lindblom, Annika, Swerdlow, Anthony ORCID: 0000-0001-5550-4159, Ziogas, Argyrios, Ekici, Arif B., Burwinkel, Barbara, Karlan, Beth Y., Nordestgaard, Borge G., Blomqvist, Carl ORCID: 0000-0003-3041-1938, Phelan, Catherine, McLean, Catriona, Pearce, Celeste Leigh, Vachon, Celine, Cybulski, Cezary, Slavov, Chavdar, Stegmaier, Christa, Maier, Christiane, Ambrosone, Christine B., Hogdall, Claus K., Teerlink, Craig C., Kang, Daehee, Tessier, Daniel C., Schaid, Daniel J., Stram, Daniel O., Cramer, Daniel W., Neal, David E., Eccles, Diana ORCID: 0000-0002-9935-3169, Flesch-Janys, Dieter, Edwards, Digna R. Velez, Wokozorczyk, Dominika, Levine, Douglas A., Yannoukakos, Drakoulis ORCID: 0000-0001-7509-3510, Sawyer, Elinor J., Bandera, Elisa V., Poole, Elizabeth M., Goode, Ellen L., Khusnutdinova, Elza, Hogdall, Estrid ORCID: 0000-0003-4689-5658, Song, Fengju, Bruinsma, Fiona, Heitz, Florian ORCID: 0000-0002-2412-0352, Modugno, Francesmary, Hamdy, Freddie C., Wiklund, Fredrik, Giles, Graham G., Olsson, Hakan ORCID: 0000-0002-8794-9635, Wildiers, Hans, Ulmer, Hans-Ulrich, Pandha, Hardev, Risch, Harvey A., Darabi, Hatef, Salvesen, Helga B., Nevanlinna, Heli, Gronberg, Henrik, Brenner, Hermann ORCID: 0000-0002-6129-1572, Brauch, Hiltrud ORCID: 0000-0001-7531-2736, Anton-Culver, Hoda, Song, Honglin, Lim, Hui-Yi, McNeish, Iain ORCID: 0000-0002-9387-7586, Campbell, Ian ORCID: 0000-0002-7773-4155, Vergote, Ignace, Gronwald, Jacek ORCID: 0000-0002-3643-2871, Lubinski, Jan ORCID: 0000-0003-2931-3003, Stanford, Janet L., Bentez, Javier, Doherty, Jennifer A., Permuth, Jennifer B., Chang-Claude, Jenny, Donovan, Jenny L., Dennis, Joe, Schildkraut, Joellen M., Schleutker, Johanna, Hopper, John L., Kupryjanczyk, Jolanta ORCID: 0000-0001-5820-0214, Park, Jong Y., Figueroa, Jonine, Clements, Judith A., Knight, Julia A., Peto, Julian, Cunningham, Julie M., Pow-Sang, Julio, Batra, Jyotsna, Czene, Kamila, Lu, Karen H., Herkommer, Kathleen, Khaw, Kay-Tee, Matsuo, Keitaro ORCID: 0000-0003-1761-6314, Muir, Kenneth, Offitt, Kenneth, Chen, Kexin, Moysich, Kirsten B., Aittomaki, Kristiina, Odunsi, Kunle, Kiemeney, Lambertus A. ORCID: 0000-0002-2368-1326, Massuger, Leon F. A. G., Fitzgerald, Liesel M., Cook, Linda S., Cannon-Albright, Lisa, Hooning, Maartje J., Pike, Malcolm C., Bolla, Manjeet K., Luedeke, Manuel, Teixeira, Manuel R., Goodman, Marc T., Schmidt, Marjanka K., Riggan, Marjorie, Aly, Markus, Rossing, Mary Anne, Beckmann, Matthias W., Moisse, Matthieu ORCID: 0000-0001-8880-9311, Sanderson, Maureen, Southey, Melissa C., Jones, Michael ORCID: 0000-0001-7479-3451, Lush, Michael, Hildebrandt, Michelle A. T., Hou, Ming-Feng ORCID: 0000-0001-6030-9702, Schoemaker, Minouk J., Garcia-Closas, Montserrat, Bogdanova, Natalia, Rahman, Nazneen ORCID: 0000-0003-4376-0440, Le, Nhu D., Orr, Nick, Wentzensen, Nicolas, Pashayan, Nora ORCID: 0000-0003-0843-2468, Peterlongo, Paolo ORCID: 0000-0001-6951-6855, Guenel, Pascal ORCID: 0000-0002-8359-518X, Brennan, Paul, Paulo, Paula ORCID: 0000-0001-8387-2127, Webb, Penelope M., Broberg, Per, Fasching, Peter A., Devilee, Peter ORCID: 0000-0002-8023-2009, Wang, Qin, Cai, Qiuyin, Li, Qiyuan, Kaneva, Radka, Butzow, Ralf, Kopperud, Reidun Kristin, Schmutzler, Rita K., Stephenson, Robert A., MacInnis, Robert J., Hoover, Robert N., Winqvist, Robert, Ness, Roberta, Milne, Roger L., Travis, Ruth C., Benlloch, Sara, Olson, Sara H., McDonnell, Shannon K., Tworoger, Shelley S., Maia, Sofi A., Berndt, Sonja, Lee, Soo Chin, Teo, Soo-Hwang, Thibodeau, Stephen N., Bojesen, Stig E., Gapstur, Susan M., Kjaer, Susanne Krueger, Pejovic, Tanja, Tammela, Teuvo L. J., Doerk, Thilo, Bruening, Thomas, Wahlfors, Tiina, Key, Tim J., Edwards, Todd L., Menon, Usha ORCID: 0000-0003-3708-1732, Hamann, Ute, Mitev, Vanio, Kosma, Veli-Matti, Setiawan, Veronica Wendy, Kristensen, Vessela, Arndt, Volker ORCID: 0000-0001-9320-8684, Vogel, Walther, Zheng, Wei ORCID: 0000-0003-1226-070X, Sieh, Weiva, Blot, William J., Kluzniak, Wojciech, Shu, Xiao-Ou, Gao, Yu-Tang, Schumacher, Fredrick ORCID: 0000-0002-3073-7463, Freedman, Matthew L., Berchuck, Andrew, Dunning, Alison M., Simard, Jacques, Haiman, Christopher A., Spurdle, Amanda, Sellers, Thomas A., Hunter, David J., Henderson, Brian E., Kraft, Peter ORCID: 0000-0002-4472-8103, Chanock, Stephen J., Couch, Fergus J., Hall, Per, Gayther, Simon A., Easton, Douglas F., Chenevix-Trench, Georgia ORCID: 0000-0002-1878-2587, Eeles, Rosalind ORCID: 0000-0002-3698-6241, Pharoah, Paul D. P. and Lambrechts, Diether ORCID: 0000-0002-3429-302X (2016). Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types. Cancer Discov., 6 (9). S. 1052 - 1068. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 2159-8290

Full text not available from this repository.

Abstract

Breast, ovarian, and prostate cancers are hormone-related and may have a shared genetic basis, but this has not been investigated systematically by genome-wide association (GWA) studies. Meta-analyses combining the largest GWA meta-analysis data sets for these cancers totaling 112,349 cases and 116,421 controls of European ancestry, all together and in pairs, identified at P < 10 -8 seven new cross-cancer loci: three associated with susceptibility to all three cancers (rs17041869/2q13/BCL2L11; rs7937840/11q12/INCENP; rs1469713/19p13/GATAD2A), two breast and ovarian cancer risk loci (rs200182588/9q31/SMC2; rs8037137/15q26/RCCD1), and two breast and prostate cancer risk loci (rs5013329/1p34/NSUN4; rs9375701/6q23/L3MBTL3). Index variants in five additional regions previously associated with only one cancer also showed clear association with a second cancer type. Cell-type-specific expression quantitative trait locus and enhancer-gene interaction annotations suggested target genes with potential cross-cancer roles at the new loci. Pathway analysis revealed significant enrichment of death receptor signaling genes near loci with P < 10(-5) in the three-cancer meta-analysis. SIGNIFICANCE: We demonstrate that combining large-scale GWA meta-analysis findings across cancer types can identify completely new risk loci common to breast, ovarian, and prostate cancers. We show that the identification of such cross-cancer risk loci has the potential to shed new light on the shared biology underlying these hormone-related cancers. (C) 2016 AACR.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Kar, Siddhartha P.UNSPECIFIEDorcid.org/0000-0002-2314-1426UNSPECIFIED
Beesley, JonathanUNSPECIFIEDorcid.org/0000-0003-1942-325XUNSPECIFIED
Al Olama, Ali AminUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Michailidou, KyriakiUNSPECIFIEDorcid.org/0000-0001-7065-1237UNSPECIFIED
Tyrer, JonathanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kote-Jarai, Zsofi A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lawrenson, KateUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lindstrom, SaraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ramus, Susan J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Thompson, Deborah J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kibel, Adam S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dansonka-Mieszkowska, AgnieszkaUNSPECIFIEDorcid.org/0000-0002-2482-6523UNSPECIFIED
Michael, AgnieszkaUNSPECIFIEDorcid.org/0000-0002-7262-6227UNSPECIFIED
Dieffenbach, Aida K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gentry-Maharaj, AleksandraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Whittemore, Alice S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wolk, AlicjaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Monteiro, AlvaroUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Peixoto, AnaUNSPECIFIEDorcid.org/0000-0002-1404-5897UNSPECIFIED
Kierzek, AndrzejUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cox, AngelaUNSPECIFIEDorcid.org/0000-0002-5138-1099UNSPECIFIED
Rudolph, AnjaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gonzalez-Neira, AnnaUNSPECIFIEDorcid.org/0000-0002-5421-2020UNSPECIFIED
Wu, Anna H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lindblom, AnnikaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Swerdlow, AnthonyUNSPECIFIEDorcid.org/0000-0001-5550-4159UNSPECIFIED
Ziogas, ArgyriosUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ekici, Arif B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Burwinkel, BarbaraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Karlan, Beth Y.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nordestgaard, Borge G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Blomqvist, CarlUNSPECIFIEDorcid.org/0000-0003-3041-1938UNSPECIFIED
Phelan, CatherineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
McLean, CatrionaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pearce, Celeste LeighUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vachon, CelineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cybulski, CezaryUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Slavov, ChavdarUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stegmaier, ChristaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Maier, ChristianeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ambrosone, Christine B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hogdall, Claus K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Teerlink, Craig C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kang, DaeheeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tessier, Daniel C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schaid, Daniel J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stram, Daniel O.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cramer, Daniel W.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Neal, David E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Eccles, DianaUNSPECIFIEDorcid.org/0000-0002-9935-3169UNSPECIFIED
Flesch-Janys, DieterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Edwards, Digna R. VelezUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wokozorczyk, DominikaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Levine, Douglas A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Yannoukakos, DrakoulisUNSPECIFIEDorcid.org/0000-0001-7509-3510UNSPECIFIED
Sawyer, Elinor J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bandera, Elisa V.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Poole, Elizabeth M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Goode, Ellen L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Khusnutdinova, ElzaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hogdall, EstridUNSPECIFIEDorcid.org/0000-0003-4689-5658UNSPECIFIED
Song, FengjuUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bruinsma, FionaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Heitz, FlorianUNSPECIFIEDorcid.org/0000-0002-2412-0352UNSPECIFIED
Modugno, FrancesmaryUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hamdy, Freddie C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wiklund, FredrikUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Giles, Graham G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Olsson, HakanUNSPECIFIEDorcid.org/0000-0002-8794-9635UNSPECIFIED
Wildiers, HansUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ulmer, Hans-UlrichUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pandha, HardevUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Risch, Harvey A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Darabi, HatefUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Salvesen, Helga B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nevanlinna, HeliUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gronberg, HenrikUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Brenner, HermannUNSPECIFIEDorcid.org/0000-0002-6129-1572UNSPECIFIED
Brauch, HiltrudUNSPECIFIEDorcid.org/0000-0001-7531-2736UNSPECIFIED
Anton-Culver, HodaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Song, HonglinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lim, Hui-YiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
McNeish, IainUNSPECIFIEDorcid.org/0000-0002-9387-7586UNSPECIFIED
Campbell, IanUNSPECIFIEDorcid.org/0000-0002-7773-4155UNSPECIFIED
Vergote, IgnaceUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gronwald, JacekUNSPECIFIEDorcid.org/0000-0002-3643-2871UNSPECIFIED
Lubinski, JanUNSPECIFIEDorcid.org/0000-0003-2931-3003UNSPECIFIED
Stanford, Janet L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bentez, JavierUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Doherty, Jennifer A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Permuth, Jennifer B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Chang-Claude, JennyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Donovan, Jenny L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dennis, JoeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schildkraut, Joellen M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schleutker, JohannaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hopper, John L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kupryjanczyk, JolantaUNSPECIFIEDorcid.org/0000-0001-5820-0214UNSPECIFIED
Park, Jong Y.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Figueroa, JonineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Clements, Judith A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Knight, Julia A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Peto, JulianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cunningham, Julie M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pow-Sang, JulioUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Batra, JyotsnaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Czene, KamilaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lu, Karen H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Herkommer, KathleenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Khaw, Kay-TeeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Matsuo, KeitaroUNSPECIFIEDorcid.org/0000-0003-1761-6314UNSPECIFIED
Muir, KennethUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Offitt, KennethUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Chen, KexinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Moysich, Kirsten B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Aittomaki, KristiinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Odunsi, KunleUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kiemeney, Lambertus A.UNSPECIFIEDorcid.org/0000-0002-2368-1326UNSPECIFIED
Massuger, Leon F. A. G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fitzgerald, Liesel M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cook, Linda S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cannon-Albright, LisaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hooning, Maartje J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pike, Malcolm C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bolla, Manjeet K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Luedeke, ManuelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Teixeira, Manuel R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Goodman, Marc T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schmidt, Marjanka K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Riggan, MarjorieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Aly, MarkusUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rossing, Mary AnneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Beckmann, Matthias W.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Moisse, MatthieuUNSPECIFIEDorcid.org/0000-0001-8880-9311UNSPECIFIED
Sanderson, MaureenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Southey, Melissa C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jones, MichaelUNSPECIFIEDorcid.org/0000-0001-7479-3451UNSPECIFIED
Lush, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hildebrandt, Michelle A. T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hou, Ming-FengUNSPECIFIEDorcid.org/0000-0001-6030-9702UNSPECIFIED
Schoemaker, Minouk J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Garcia-Closas, MontserratUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bogdanova, NataliaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rahman, NazneenUNSPECIFIEDorcid.org/0000-0003-4376-0440UNSPECIFIED
Le, Nhu D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Orr, NickUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wentzensen, NicolasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pashayan, NoraUNSPECIFIEDorcid.org/0000-0003-0843-2468UNSPECIFIED
Peterlongo, PaoloUNSPECIFIEDorcid.org/0000-0001-6951-6855UNSPECIFIED
Guenel, PascalUNSPECIFIEDorcid.org/0000-0002-8359-518XUNSPECIFIED
Brennan, PaulUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Paulo, PaulaUNSPECIFIEDorcid.org/0000-0001-8387-2127UNSPECIFIED
Webb, Penelope M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Broberg, PerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fasching, Peter A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Devilee, PeterUNSPECIFIEDorcid.org/0000-0002-8023-2009UNSPECIFIED
Wang, QinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cai, QiuyinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Li, QiyuanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kaneva, RadkaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Butzow, RalfUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kopperud, Reidun KristinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schmutzler, Rita K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stephenson, Robert A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
MacInnis, Robert J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hoover, Robert N.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Winqvist, RobertUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ness, RobertaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Milne, Roger L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Travis, Ruth C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Benlloch, SaraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Olson, Sara H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
McDonnell, Shannon K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tworoger, Shelley S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Maia, Sofi A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Berndt, SonjaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lee, Soo ChinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Teo, Soo-HwangUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Thibodeau, Stephen N.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bojesen, Stig E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gapstur, Susan M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kjaer, Susanne KruegerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pejovic, TanjaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tammela, Teuvo L. J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Doerk, ThiloUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bruening, ThomasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wahlfors, TiinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Key, Tim J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Edwards, Todd L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Menon, UshaUNSPECIFIEDorcid.org/0000-0003-3708-1732UNSPECIFIED
Hamann, UteUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mitev, VanioUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kosma, Veli-MattiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Setiawan, Veronica WendyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kristensen, VesselaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Arndt, VolkerUNSPECIFIEDorcid.org/0000-0001-9320-8684UNSPECIFIED
Vogel, WaltherUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Zheng, WeiUNSPECIFIEDorcid.org/0000-0003-1226-070XUNSPECIFIED
Sieh, WeivaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Blot, William J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kluzniak, WojciechUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Shu, Xiao-OuUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gao, Yu-TangUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schumacher, FredrickUNSPECIFIEDorcid.org/0000-0002-3073-7463UNSPECIFIED
Freedman, Matthew L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Berchuck, AndrewUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dunning, Alison M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Simard, JacquesUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Haiman, Christopher A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Spurdle, AmandaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sellers, Thomas A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hunter, David J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Henderson, Brian E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kraft, PeterUNSPECIFIEDorcid.org/0000-0002-4472-8103UNSPECIFIED
Chanock, Stephen J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Couch, Fergus J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hall, PerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gayther, Simon A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Easton, Douglas F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Chenevix-Trench, GeorgiaUNSPECIFIEDorcid.org/0000-0002-1878-2587UNSPECIFIED
Eeles, RosalindUNSPECIFIEDorcid.org/0000-0002-3698-6241UNSPECIFIED
Pharoah, Paul D. P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lambrechts, DietherUNSPECIFIEDorcid.org/0000-0002-3429-302XUNSPECIFIED
URN: urn:nbn:de:hbz:38-265407
DOI: 10.1158/2159-8290.CD-15-1227
Journal or Publication Title: Cancer Discov.
Volume: 6
Number: 9
Page Range: S. 1052 - 1068
Date: 2016
Publisher: AMER ASSOC CANCER RESEARCH
Place of Publication: PHILADELPHIA
ISSN: 2159-8290
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
TRAIL-INDUCED APOPTOSIS; PASSENGER COMPLEX CPC; BIOLOGICAL PATHWAYS; ENRICHMENT ANALYSIS; DEATH RECEPTORS; RISK LOCI; VARIANTS; CELLS; POPULATION; PROFILESMultiple languages
OncologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/26540

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