Universität zu Köln

Lenssen, R. and Liekweg, A. (2016). Strategies of age-adapted pharmacotherapy in renal failure. Z. Gerontol. Geriatr., 49 (6). S. 494 - 500. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1435-1269

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Abstract

Many geriatric patients with multimorbidities have an increased risk for impaired renal function due to age and often the presence of comorbidities, such as diabetes mellitus, hypertension and heart failure. This impairment in kidney function in turn necessitates adjustments in drug therapy. A successful strategy for treating these patients includes treatment of the underlying diseases, a comprehensive review of the indications, selection of appropriate pharmacotherapeutic alternatives and for some drugs dose adjustment to the renal function. To achieve therapeutic success many patient individual factors, such as potentially complex medication regimens, polypharmacy, cognitive function and functional disabilities need to be considered when prescribing medications. This article describes the problems associated with drug therapy that is not adjusted to renal function and provides guidelines for assessment of the benefits and risks in patients with kidney failure. The characteristic features of geriatric patients in particular are considered and discussed.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Lenssen, R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Liekweg, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-267830
DOI:	10.1007/s00391-016-1111-4
Journal or Publication Title:	Z. Gerontol. Geriatr.
Volume:	49
Number:	6
Page Range:	S. 494 - 500
Date:	2016
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1435-1269
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ADVERSE DRUG EVENTS; KIDNEY-FUNCTION; MEDICATIONS; RISK Multiple languages Geriatrics & Gerontology; Gerontology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/26783