Universität zu Köln

Schaub, F., Hos, D., Bucher, F., Siebelmann, S., Bachmann, B. O. and Cursiefen, C. (2016). Boston-keratoprosthesis. Preliminary experiences in 13 high-risk eyes from the Department of Ophthalmology of the University of Cologne. Ophthalmologe, 113 (6). S. 492 - 500. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-0423

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Abstract

Background. Corneal transplantation in high-risk eyes remains a challenge. The Boston keratoprosthesis (B-KPro) is a final option for patients with end-stage corneal disease and a poor prognosis with conventional penetrating keratoplasty. In this article the results of the first 13 eyes that received a B-KPro type I at the Department of Ophthalmology, University of Cologne, Germany are reported and the usefulness of postoperative slit-lamp optical coherence tomography (SL-OCT) for control purposes is evaluated. Material and methods. All recipients of a B-KPro type I between September 2013 and May 2015 were included in the study. The feasibility of the operation, clinical outcomes, complications and revision surgery were investigated. The visualization of wound healing by SL-OCT was analyzed. Results. The age of the patients ranged from 26 to 92 years (mean 57.3 +/- 20.9 years). In all 13 eyes from 12 patients (6 males and 6 females) dense corneal opacification with vascularization and sometimes also conjunctivalization was present. Preoperative visual acuity was reduced and ranged from mere light perception up to a maximum of 1/35 eye chart. All 13 eyes could be supplied with a B-KPro type I without any intraoperative complications, in 6 eyes no significant postoperative complications occurred, whereas in 7 eyes various additional surgical interventions were required and 1 B-KPro could not be preserved. Postoperative visual acuity ranged from light perception to 20/32 and was significantly improved in 85 % of the treated eyes. The use of SL-OCT reproducibly allowed the postoperative assessment of stromal thinning. Conclusion. The B-KPro provides the possibility of visual rehabilitation in high-risk eyes that could never be achieved without artificial cornea replacement. Despite higher complication rates this technique represents a significant progress in the surgical treatment of complex corneal pathologies. Regular and intensive postoperative controls are necessary to achieve good long-term results.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schaub, F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hos, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bucher, F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Siebelmann, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bachmann, B. O. UNSPECIFIED UNSPECIFIED UNSPECIFIED Cursiefen, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-273289
DOI:	10.1007/s00347-015-0209-1
Journal or Publication Title:	Ophthalmologe
Volume:	113
Number:	6
Page Range:	S. 492 - 500
Date:	2016
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1433-0423
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language LONG-TERM OUTCOMES; ENDOTHELIAL KERATOPLASTY; TYPE-1 KERATOPROSTHESIS; CROSS-LINKING; COMPLICATIONS; MULTICENTER; MANAGEMENT; MEMBRANE; DMEK Multiple languages Ophthalmology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/27328