Universität zu Köln

Luecken, Leonhard, Popovych, Oleksandr V., Tass, Peter A. and Yanchuk, Serhiy ORCID: 0000-0003-1628-9569 (2016). Noise-enhanced coupling between two oscillators with long-term plasticity. Phys. Rev. E, 93 (3). COLLEGE PK: AMER PHYSICAL SOC. ISSN 2470-0053

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Abstract

Spike timing-dependent plasticity is a fundamental adaptation mechanism of the nervous system. It induces structural changes of synaptic connectivity by regulation of coupling strengths between individual cells depending on their spiking behavior. As a biophysical process its functioning is constantly subjected to natural fluctuations. We study theoretically the influence of noise on a microscopic level by considering only two coupled neurons. Adopting a phase description for the neurons we derive a two-dimensional system which describes the averaged dynamics of the coupling strengths. We show that a multistability of several coupling configurations is possible, where some configurations are not found in systems without noise. Intriguingly, it is possible that a strong bidirectional coupling, which is not present in the noise-free situation, can be stabilized by the noise. This means that increased noise, which is normally expected to desynchronize the neurons, can be the reason for an antagonistic response of the system, which organizes itself into a state of stronger coupling and counteracts the impact of noise. This mechanism, as well as a high potential for multistability, is also demonstrated numerically for a coupled pair of Hodgkin-Huxley neurons.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Luecken, Leonhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Popovych, Oleksandr V. UNSPECIFIED UNSPECIFIED UNSPECIFIED Tass, Peter A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Yanchuk, Serhiy UNSPECIFIED orcid.org/0000-0003-1628-9569 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-281658
DOI:	10.1103/PhysRevE.93.032210
Journal or Publication Title:	Phys. Rev. E
Volume:	93
Number:	3
Date:	2016
Publisher:	AMER PHYSICAL SOC
Place of Publication:	COLLEGE PK
ISSN:	2470-0053
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language COORDINATED RESET NEUROMODULATION; TIMING-DEPENDENT PLASTICITY; SYNAPTIC MODIFICATION; DYNAMICS; SYNCHRONY; CONNECTIVITY; STIMULATION; NETWORKS; TINNITUS; NEURONS Multiple languages Physics, Fluids & Plasmas; Physics, Mathematical Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/28165