Universität zu Köln

Herff, H., Schneider, A., Schroeder, D., Wetsch, W. and Boettiger, B. W. (2016). Therapeutic hypothermia in 2015. Influence of the TTM study on the intensive care procedure after cardiac arrest. Med. Klin.-Intensivmed Notfallmed., 111 (1). S. 47 - 52. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 2193-6226

Full text not available from this repository.

Abstract

In the 1960s, Peter Safar et al. postulated the benefit of postcardiac arrest hypothermia after successful cardiopulmonary resuscitation (CPR). However, therapeutic hypothermia postCPR did not become a standard procedure until the first few years of the new millennium. Various noninvasive and invasive cooling methods are available. Generally, more invasive cooling methods are more effective-but also tend to involve more complications. Furthermore, invasive measures need more time and thus may be instituted late in the postCPR process, delaying the cooling efforts in the initial phase. There is ongoing controversy about when best to commence cooling. Recent studies of initial out-of-hospital cooling did not show any benefit for the patients compared to starting cooling in the hospital. The exact target temperature is the subject of multiple ongoing discussions. A recent study showed no disadvantage of cooling to 36 aintegral compared to 33 aintegral, which is in the widely accepted standard target temperature range of 32-34 aintegral. Nevertheless, cooling to 32-34 aintegral according to the 2010 guidelines is still the accepted standard procedure unless and until new studies generate more evidence. The European Resuscitation Council has given advance notice of a statement on the optimal target temperature in the near future. Finally, large registry studies have demonstrated the benefit of combining postCPR hypothermia with early percutaneous cardiac interventions (PCI) in acute coronary syndromes, which are often a cause of cardiac arrest. Transport of patients after CPR to specialized postcardiac arrest centres with the possibility of acute PCI and cooling, comparable to the transfer of multiple trauma patients to trauma centres, may be beneficial.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Herff, H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schneider, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schroeder, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wetsch, W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Boettiger, B. W. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-285688
DOI:	10.1007/s00063-015-0009-z
Journal or Publication Title:	Med. Klin.-Intensivmed Notfallmed.
Volume:	111
Number:	1
Page Range:	S. 47 - 52
Date:	2016
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	2193-6226
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ADVANCED LIFE-SUPPORT; COMATOSE SURVIVORS; VENTRICULAR-FIBRILLATION; MILD HYPOTHERMIA; RESUSCITATION; INDUCTION Multiple languages Medicine, General & Internal Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/28568