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Koneti, Raslova, Hana ORCID: 0000-0001-8846-5299, Rebulla, Paolo ORCID: 0000-0002-3875-5754, Rees, David, Ribrag, Vincent, Rijneveld, Anita, Rinalducci, Sara, Robak, Tadeusz, Roberts, Irene, Rodrigues, Charlene ORCID: 0000-0003-0942-3707, Rosendaal, Frits, Rosenwald, Andreas, Rule, Simon, Russo, Roberta ORCID: 0000-0002-3624-7721, Saglio, Guiseppe, Sanchez, Mayka ORCID: 0000-0002-6499-5989, Scharf, Ruediger E., Schlenke, Peter, Semple, John, Sierra, Jorge, So-Osman, Cynthia, Manuel Soria, Jose, Stamatopoulos, Kostas, Stegmayr, Bernd, Stunnenberg, Henk, Swinkels, Dorine, Taborda Barata, Joao Pedro, Taghon, Tom, Taher, Ali, Terpos, Evangelos, Thachil, Jecko, Tissot, Jean Daniel ORCID: 0000-0003-2493-8469, Touw, Ivo, Toye, Ash, Trappe, Ralf ORCID: 0000-0001-7565-7160, Traverse-Glehen, Alexandra, Unal, Sule, Vaulont, Sophie, Viprakasit, Vip, Vitolo, Umberto, van Wijk, Richard, Wojtowicz, Agnieszka, Zeerleder, Sacha and Zieger, Barbara (2016). The European Hematology Association Roadmap for European Hematology Research: a consensus document. Haematologica, 101 (2). S. 115 - 209. PAVIA: FERRATA STORTI FOUNDATION. ISSN 0390-6078

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Abstract

The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at (sic)23 billion per year, a level of cost that is not matched in current European hematology research funding. In recent decades, hematology research has improved our fundamental understanding of the biology of blood disorders, and has improved diagnostics and treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap. The EHA Roadmap identifies nine 'sections' in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders. The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Engert, AndreasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Balduini, CarloUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Brand, AnnekeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
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Cordonnier, CatherineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
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de Wit, Thom DuyveneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
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de Haas, FleurUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
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Jaffredo, ThierryUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
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Schuringa, Jan JacobUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
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Stauder, ReinhardUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stilgenbauer, StephanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tamary, HannahUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Theilgaard-Monch, KimUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Thein, Swee LayUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
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Trneny, MarekUNSPECIFIEDorcid.org/0000-0002-6952-6073UNSPECIFIED
Vainchenker, WilliamUNSPECIFIEDorcid.org/0000-0003-4705-202XUNSPECIFIED
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Rao, A. KonetiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
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Rijneveld, AnitaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
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Rule, SimonUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Russo, RobertaUNSPECIFIEDorcid.org/0000-0002-3624-7721UNSPECIFIED
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Scharf, Ruediger E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schlenke, PeterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Semple, JohnUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sierra, JorgeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
So-Osman, CynthiaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Manuel Soria, JoseUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stamatopoulos, KostasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stegmayr, BerndUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stunnenberg, HenkUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Swinkels, DorineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Taborda Barata, Joao PedroUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
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Viprakasit, VipUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vitolo, UmbertoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
van Wijk, RichardUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
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Zieger, BarbaraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-286270
DOI: 10.3324/haematol.2015.136739
Journal or Publication Title: Haematologica
Volume: 101
Number: 2
Page Range: S. 115 - 209
Date: 2016
Publisher: FERRATA STORTI FOUNDATION
Place of Publication: PAVIA
ISSN: 0390-6078
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
ACUTE MYELOID-LEUKEMIA; THROMBOTIC THROMBOCYTOPENIC PURPURA; STEM-CELL TRANSPLANTATION; PERIPHERAL T-CELL; CHRONIC LYMPHOCYTIC-LEUKEMIA; NEONATAL ALLOIMMUNE THROMBOCYTOPENIA; PATHOGEN INACTIVATION TECHNOLOGIES; COMPLEMENT INHIBITOR ECULIZUMAB; RABBIT ANTITHYMOCYTE GLOBULIN; CONVENTIONAL CARE REGIMENSMultiple languages
HematologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/28627

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