Universität zu Köln

Manegold-Brauer, Gwendolin ORCID: 0000-0003-4292-6779, Oseledchyk, Anton, Floeck, Anne, Berg, Christoph, Gembruch, Ulrich ORCID: 0000-0001-8284-4669 and Geipel, Annegret (2016). Approach to the sonographic evaluation of fetal ventriculomegaly at 11 to 14 weeks gestation. BMC Pregnancy Childbirth, 16. LONDON: BMC. ISSN 1471-2393

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Abstract

Background: The aim of the study was to report the prevalence and associated findings of fetal ventriculomegaly between 11 + 0 and 13 + 6 gestational weeks and to evaluate a sonographic approach to classify first trimester ventriculomegaly in the standard axial plane used for biparietal diameter (BPD) measurement. Methods: The ratio between choroid plexus and lateral ventricle diameter (PDVDR), between the choroid plexus and lateral ventricle length (PLVLR) and between the choroid plexus and lateral ventricle area (PAVAR) were calculated from stored 2D images of the axial head plane in 100 normal fetuses and 17 fetuses with ventriculomegaly. Results: The PDVDR, the PLVLR and the PAVAR were below the 5(th) percentile in 82.4 %, 94.1 % and 94.1 % of the cases with ventriculomegaly. Ventriculomegaly was isolated in 29.4 % and associated with further anomalies in 70.6 % at the initial evaluation. The mean PLVLR in euploid compared to aneuploid fetuses was significantly lower (0.40 versus 0.53 (p = 0.0332)). Conclusions: The measurements of PDVDR, PLVLR and PAVAR are helpful to objectify ventriculomegaly at 11-14 gestational weeks. The PLVLR and PAVAR were superior to PDVDR, since there seems to be rather shrinkage of the choroid plexus than an increased width of the lateral ventricles in the first trimester.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Manegold-Brauer, Gwendolin UNSPECIFIED orcid.org/0000-0003-4292-6779 UNSPECIFIED Oseledchyk, Anton UNSPECIFIED UNSPECIFIED UNSPECIFIED Floeck, Anne UNSPECIFIED UNSPECIFIED UNSPECIFIED Berg, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED Gembruch, Ulrich UNSPECIFIED orcid.org/0000-0001-8284-4669 UNSPECIFIED Geipel, Annegret UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-287312
DOI:	10.1186/s12884-016-0797-z
Journal or Publication Title:	BMC Pregnancy Childbirth
Volume:	16
Date:	2016
Publisher:	BMC
Place of Publication:	LONDON
ISSN:	1471-2393
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language OPEN SPINA-BIFIDA; STRUCTURAL ABNORMALITIES; POSTERIOR BRAIN; FETUSES; DIAGNOSIS Multiple languages Obstetrics & Gynecology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/28731