Gianolio, Eleonora, Mohan, Resmi and Berkessel, Albrecht ORCID: 0000-0003-0470-7428 (2016). Enantiopure N-Benzyloxycarbonyl-beta(2)-amino Acid Allyl Esters from Racemic beta-Lactams by Dynamic Kinetic Resolution using Candida antarctica Lipase B. Adv. Synth. Catal., 358 (1). S. 30 - 34. WEINHEIM: WILEY-V C H VERLAG GMBH. ISSN 1615-4169
Full text not available from this repository.Abstract
The dynamic kinetic resolution of alpha-substituted racemic beta-lactams by alcoholytic ring-opening, catalyzed by immobilized lipase B from Candida antarctica is described. With this process, a variety of racemic a-substituted N-Cbz-azetidinones (Cbz = benzyloxycarbonyl) was transformed to the corresponding N-Cbz-protected beta(2)-amino acid allyl esters with high enantioselectivity (up to 99%) and high yields (up to quantitative) at room temperature.
Item Type: | Journal Article | ||||||||||||||||
Creators: |
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URN: | urn:nbn:de:hbz:38-287569 | ||||||||||||||||
DOI: | 10.1002/adsc.201500820 | ||||||||||||||||
Journal or Publication Title: | Adv. Synth. Catal. | ||||||||||||||||
Volume: | 358 | ||||||||||||||||
Number: | 1 | ||||||||||||||||
Page Range: | S. 30 - 34 | ||||||||||||||||
Date: | 2016 | ||||||||||||||||
Publisher: | WILEY-V C H VERLAG GMBH | ||||||||||||||||
Place of Publication: | WEINHEIM | ||||||||||||||||
ISSN: | 1615-4169 | ||||||||||||||||
Language: | English | ||||||||||||||||
Faculty: | Faculty of Mathematics and Natural Sciences | ||||||||||||||||
Divisions: | Faculty of Mathematics and Natural Sciences > Department of Chemistry > Institute of Organic Chemistry | ||||||||||||||||
Subjects: | no entry | ||||||||||||||||
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Refereed: | Yes | ||||||||||||||||
URI: | http://kups.ub.uni-koeln.de/id/eprint/28756 |
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