Universität zu Köln

Draga, Margarethe, Scaal, Martin and Proels, Felicitas (2016). Signaling filopodia in avian embryogenesis: formation and function. AIMS Mol. Sci., 3 (4). S. 683 - 692. SPRINGFIELD: AMER INST MATHEMATICAL SCIENCES-AIMS. ISSN 2372-0301

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Abstract

In vertebrates and invertebrates specialized cellular protrusions, called signaling filopodia or cytonemes, play an important role in cell-cell communication by carrying receptors and ligands to distant cells to activate various signaling pathways. In the chicken embryo, signaling filopodia were described in limb bud mesenchyme and in somite epithelia. The formation of signaling filopodia depends on the activity of Rho GTPases and reorganization of the cytoskeleton. Here, we give a short overview on the present knowledge on avian signaling filopodia and discuss the molecular basis of cytoskeletal rearrangements leading to filopodia formation.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Draga, Margarethe UNSPECIFIED UNSPECIFIED UNSPECIFIED Scaal, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Proels, Felicitas UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-288284
DOI:	10.3934/molsci.2016.4.683
Journal or Publication Title:	AIMS Mol. Sci.
Volume:	3
Number:	4
Page Range:	S. 683 - 692
Date:	2016
Publisher:	AMER INST MATHEMATICAL SCIENCES-AIMS
Place of Publication:	SPRINGFIELD
ISSN:	2372-0301
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ACTIN CYTOSKELETON; RHO GTPASES; VERTEBRATE GASTRULATION; FASCIN FUNCTION; MECHANISM; CYTONEMES; TRANSPORT; PROTEINS; CELLS; NUCLEATION Multiple languages Biochemistry & Molecular Biology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/28828