Universität zu Köln

Stenner, Markus, Beenen, Franziska, Hahn, Moritz, Koopmann, Mario, Weiss, Daniel and Huettenbrink, Karl-Bernd (2016). Exploratory study of long-term health-related quality of life in patients with surgically treated primary parotid gland cancer. Head Neck-J. Sci. Spec. Head Neck, 38 (1). S. 111 - 118. HOBOKEN: WILEY. ISSN 1097-0347

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Abstract

Background. Health-related quality of life (HRQOL) has received more and more attention as an outcome in cancer therapy. In this exploratory study, we assessed the long-term HRQOL among 77 surgically treated patients with parotid gland cancer. Methods. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30-questions (EORTC-QLQ-C30) and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 Head and Neck 35-questions (EORTC-QLQ-C30-H&N35) questionnaires were used in a cross-sectional design. The mean time-lag between initial diagnosis and completion of the questionnaire was 89.7 months. Results. The HRQOL significantly increased with the time-lag to surgery and decreased with the patients' age. Factors with clinically significant effects in several areas of long-term HRQOL (ie, more than 4 scores) were age, type of neck dissection, preoperative facial nerve palsy, and postoperative radiation therapy. Conclusion. In parotid gland cancer surgery, factors, such as sex, age, type of surgery, facial nerve palsy, and radiation therapy, seem to be associated with clinically meaningful differences in long-term HRQOL scores. (C) 2015 Wiley Periodicals, Inc.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Stenner, Markus UNSPECIFIED UNSPECIFIED UNSPECIFIED Beenen, Franziska UNSPECIFIED UNSPECIFIED UNSPECIFIED Hahn, Moritz UNSPECIFIED UNSPECIFIED UNSPECIFIED Koopmann, Mario UNSPECIFIED UNSPECIFIED UNSPECIFIED Weiss, Daniel UNSPECIFIED UNSPECIFIED UNSPECIFIED Huettenbrink, Karl-Bernd UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-291497
DOI:	10.1002/hed.23858
Journal or Publication Title:	Head Neck-J. Sci. Spec. Head Neck
Volume:	38
Number:	1
Page Range:	S. 111 - 118
Date:	2016
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1097-0347
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EUROPEAN-ORGANIZATION; EORTC QLQ-H-AND-N35; QUESTIONNAIRE; CARCINOMA; SURGERY; HEAD; RADIOTHERAPY; OUTCOMES; QLQ-C30; IMPACT Multiple languages Otorhinolaryngology; Surgery Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/29149