Kresken, M., Koerber-Irrgang, B., Biedenbach, D. J., Batista, N., Besard, V., Canton, R., Garcia-Castillo, M., Kalka-Moll, W., Pascual, A., Schwarz, R., Van Meensel, B., Wisplinghoff, H. and Seifert, H. (2016). Comparative in vitro activity of oral antimicrobial agents against Enterobacteriaceae from patients with community-acquired urinary tract infections in three European countries. Clin. Microbiol. Infect., 22 (1). OXFORD: ELSEVIER SCI LTD. ISSN 1469-0691

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Abstract

Enterobacteriaceae causing community-acquired urinary tract infections were examined in selected outpatient clinics and hospitals in Belgium, Germany and Spain using EUCAST breakpoints for susceptibility. A total of 1190 isolates were collected. Escherichia coli isolates were resistant to amoxicillin-clavulanic acid (28.1%), ciprofloxacin (23.4%) and trimethoprim-sulfamethoxazole (21.4%) compared with fosfomycin and nitrofurantoin (each, < 1.5%). Ceftibuten (MIC50/90 0.25/0.5 mg/L) and ceftriaxone activity (MIC50/90 <= 0.25 mg/L) was comparable. Ceftibuten (MIC90 <= 0.25 mg/L) was also active against Proteus mirabilis and Klebsiella spp. Extended-spectrum beta-lactamase phenotypes were 7.1% for E. coli, 5.6% for Klebsiella pneumoniae and 0.4% for P. mirabilis. Resistance was common among men and elderly women. (C) 2015 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Kresken, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Koerber-Irrgang, B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Biedenbach, D. J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Batista, N.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Besard, V.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Canton, R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Garcia-Castillo, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kalka-Moll, W.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pascual, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schwarz, R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Van Meensel, B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wisplinghoff, H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Seifert, H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-292524
DOI: 10.1016/j.cmi.2015.08.019
Journal or Publication Title: Clin. Microbiol. Infect.
Volume: 22
Number: 1
Date: 2016
Publisher: ELSEVIER SCI LTD
Place of Publication: OXFORD
ISSN: 1469-0691
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
ESCHERICHIA-COLI; BETA-LACTAMASES; RESISTANCE; SUSCEPTIBILITY; TRIMETHOPRIM; ANTIBIOTICS; EVOLUTION; THERAPYMultiple languages
Infectious Diseases; MicrobiologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/29252

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