Universität zu Köln

Middelstaedt, Jennifer, Folkerts, Ann-Kristin, Blawath, Sabrina and Kalbe, Elke (2016). Cognitive Stimulation for People with Dementia in Long-Term Care Facilities: Baseline Cognitive Level Predicts Cognitive Gains, Moderated by Depression. J. Alzheimers Dis., 54 (1). S. 253 - 269. AMSTERDAM: IOS PRESS. ISSN 1875-8908

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Abstract

Background: Increasing evidence demonstrates the efficacy of cognitive stimulation (CS) in individuals with dementia. However, conducting studies in nursing homes engenders specific challenges that have limited the data gathered on this topic so far. Objective: The aim of this randomized controlled trial was to investigate the effects of CS on cognition, quality of life (QoL), behavioral symptoms, and activities of daily life in persons with dementia living in nursing homes. We further aimed to identify predictors of the intervention's benefits. Methods: Seventy-one persons with mild to moderate dementia were randomly allocated to the experimental group (EG; n = 36) that visited a CS program twice weekly for eight weeks or to the control group (CG; n = 35) that was receiving usual care. Neuropsychological tests were conducted before and after the intervention period and at six-week follow-up. Results: There were no significant interaction effects Time x Group for the outcome measures. However, regression analysis revealed that a low cognitive baseline level predicted cognitive improvements. Furthermore, a low baseline level of QoL predicted a QoL benefit. For both findings, depression was a significant moderator, meaning that persons with fewer depressive symptoms had a higher probability of showing improvements. Conclusion: This study provides data on profiles of patients who are most likely to profit from CS intervention in nursing-home settings and demonstrates that treatment of depression is of the utmost relevance for a positive outcome of CS. Living conditions will have to be considered more thoroughly in future research.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Middelstaedt, Jennifer UNSPECIFIED UNSPECIFIED UNSPECIFIED Folkerts, Ann-Kristin UNSPECIFIED UNSPECIFIED UNSPECIFIED Blawath, Sabrina UNSPECIFIED UNSPECIFIED UNSPECIFIED Kalbe, Elke UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-292823
DOI:	10.3233/JAD-160181
Journal or Publication Title:	J. Alzheimers Dis.
Volume:	54
Number:	1
Page Range:	S. 253 - 269
Date:	2016
Publisher:	IOS PRESS
Place of Publication:	AMSTERDAM
ISSN:	1875-8908
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language NURSING-HOME RESIDENTS; RANDOMIZED CONTROLLED-TRIAL; QUALITY-OF-LIFE; OLDER-ADULTS; ALZHEIMERS-DISEASE; DEGENERATIVE DEMENTIA; CLINICAL-SIGNIFICANCE; REMINISCENCE THERAPY; INTERVENTION; EFFICACY Multiple languages Neurosciences Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/29282