Universität zu Köln

Ludwar, Lena, Mannel, Hilke, Hamacher, Stefanie, Noack, Michael Johannes and Barbe, Anna Greta . Oil pulling to relieve medication-induced xerostomia: A randomized, single-blind, crossover trial. Oral Dis.. HOBOKEN: WILEY. ISSN 1601-0825

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Abstract

Objectives To determine the subjective effectiveness of oilpulling on medication-induced xerostomia with regard to symptom relief, quality of life, taste, mucosal moisture and oral parameters. Materials and Methods In a randomized, single-blind, crossover trial in participants with medication-induced xerostomia (n = 26; mean age 64.71 (standard deviation (SD) 15.60) years), we investigated oilpulling efficacy (sunflower oil) versus mineral water after one-week use. Xerostomic burden (visual analogue scale, VAS), symptom relief and oral examinations (gingivitis index, plaque index, whole stimulated and unstimulated salivation rates) were investigated at baseline and the end of the follow-up. Results Oilpulling reduced the xerostomic burden (baseline value 6.46 (SD 1.80), decreasing to 4.93 (SD 2.97)) (p = .003), without difference between oil versus water (p = .067). Baseline values for water were 6.08 (SD 2.17) decreasing to 5.72 (SD 2.17) (p = .124). Compared to water, oil made swallowing easier (p = .031), caused a pleasant mouthfeel (p = .031) and caused less waking up at night (p = .031). Effectiveness (p = .002) and duration (p = .007) of symptom relief showed differences between products in favour of oil. Conclusions Oil pulling alleviated the overall xerostomic burden. In the comparison between oil and water, no difference regarding symptom relief could be shown. Patients should be informed of possibilities and limitations of oilpulling as inexpensive and easy-to-obtain alternative to commercially available products for short-term symptom relief.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Ludwar, Lena UNSPECIFIED UNSPECIFIED UNSPECIFIED Mannel, Hilke UNSPECIFIED UNSPECIFIED UNSPECIFIED Hamacher, Stefanie UNSPECIFIED UNSPECIFIED UNSPECIFIED Noack, Michael Johannes UNSPECIFIED UNSPECIFIED UNSPECIFIED Barbe, Anna Greta UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-307704
DOI:	10.1111/odi.13752
Journal or Publication Title:	Oral Dis.
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1601-0825
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SALIVARY-GLAND DYSFUNCTION; DRY MOUTH; WORLD WORKSHOP; WHOLE SALIVA; SYMPTOMS; EFFICACY; LACTOPEROXIDASE; RADIOTHERAPY; MULTICENTER; SUBSTITUTES Multiple languages Dentistry, Oral Surgery & Medicine Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/30770