Universität zu Köln

Peinemann, Frank, Harari, Marco, Peternel, Sandra, Chan, Thalia, Chan, David, Labeit, Alexander M. and Gambichler, Thilo ORCID: 0000-0001-7862-3695 . Indoor balneophototherapy for chronic plaque psoriasis: Abridged Cochrane Review. Dermatol. Ther.. HOBOKEN: WILEY. ISSN 1529-8019

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Abstract

Artificial exposure to ultraviolet B light (UVB) while soaking in an indoor salt bath, also called balneophototherapy, could simulate the natural exposure to the sun while bathing in the Dead Sea. We aimed to assess the effects of this intervention on patients with chronic plaque psoriasis. We searched CENTRAL, MEDLINE, Embase, and LILACS up to June 2019. We included randomized controlled trials (RCTs). The primary efficacy outcome was psoriasis area and severity index (PASI)-75 to detect people with a 75% or more reduction in the PASI score from baseline. The primary adverse outcome was treatment-related adverse events requiring withdrawal. We included eight RCTs (2105 participants; 1976 analyzed). With respect to PASI-75, two studies found that salt bath + UVB may improve psoriasis when compared to UVB alone (risk ratio 1.71, 95% confidence interval 1.24 to 2.35; 278 participants). With respect to treatment-related adverse events requiring withdrawal, two other studies found little to no difference when compared to UVB alone (risk ratio 0.96, 95% confidence interval 0.35 to 2.64; 404 participants). Salt bath + UVB could improve psoriasis when compared to UVB alone, though, results are based on a limited number of studies and provide low-certainty evidence.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Peinemann, Frank UNSPECIFIED UNSPECIFIED UNSPECIFIED Harari, Marco UNSPECIFIED UNSPECIFIED UNSPECIFIED Peternel, Sandra UNSPECIFIED UNSPECIFIED UNSPECIFIED Chan, Thalia UNSPECIFIED UNSPECIFIED UNSPECIFIED Chan, David UNSPECIFIED UNSPECIFIED UNSPECIFIED Labeit, Alexander M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Gambichler, Thilo UNSPECIFIED orcid.org/0000-0001-7862-3695 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-308864
DOI:	10.1111/dth.14588
Journal or Publication Title:	Dermatol. Ther.
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1529-8019
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SALINE SPA WATER; RANDOMIZED CONTROLLED-TRIAL; BAND ULTRAVIOLET-B; SALT-WATER; UV-B; BATHS; MODERATE Multiple languages Dermatology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/30886