Universität zu Köln

Oikonomidis, Stavros, Greven, Johannes, Bredow, Jan, Eh, Madita, Prescher, Andreas, Fischer, Horst, Thuering, Johannes, Eysel, Peer, Hildebrand, Frank, Kobbe, Philipp, Scheyerer, Max Joseph and Herren, Christian (2020). Biomechanical effects of posterior pedicle screw-based instrumentation using titanium versus carbon fiber reinforced PEEK in an osteoporotic spine human cadaver model. Clin. Biomech., 80. OXFORD: ELSEVIER SCI LTD. ISSN 1879-1271

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Abstract

Background: Aim of this biomechanical investigation was to compare the biomechanical effects of a carbon fiber reinforced PEEK and titanium pedicle screw/rod device in osteoporotic human cadaveric spine. Methods: Ten human fresh-frozen cadaveric lumbar spines (L1-L5) have been used and were randomized into two groups according to the bone mineral density. A monosegmental posterior instrumentation (L3-L4) using titanium pedicle screws and rods was carried out in group A and using carbon fiber reinforced PEEK in group B. A cyclic loading test was performed at a frequency of 3 Hz, starting with a peak of 500 N for the first 2000 cycles, up to 950 N for 100,000 cycles under a general preload with 100 N. All specimens were evaluated with regard to a potential collapse of the implanted pedicle screws. A CT supported digital measurement of cavities around the pedicle at 3 defined measuring points was performed. Finally, the maximum zero-time failure load of all specimens was determined using a universal testing machine (80% F-max). Findings: Regarding maximum axial force (group A: 2835 N, group B: 3006 N, p = 0.595) and maximum compression (group A: 11.67 mm, group B: 15.15 mm, p = 0.174) no statistical difference could be shown between the two groups. However, significant smaller cavity formation around the pedicle screws could be observed in group B (p = 0.007), especially around the screw tip (p < 0.001). Interpretation: Carbon fiber reinforced PEEK devices seem to be advantageous in terms of microscopic screw loosening compared to titanium devices.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Oikonomidis, Stavros UNSPECIFIED UNSPECIFIED UNSPECIFIED Greven, Johannes UNSPECIFIED UNSPECIFIED UNSPECIFIED Bredow, Jan UNSPECIFIED UNSPECIFIED UNSPECIFIED Eh, Madita UNSPECIFIED UNSPECIFIED UNSPECIFIED Prescher, Andreas UNSPECIFIED UNSPECIFIED UNSPECIFIED Fischer, Horst UNSPECIFIED UNSPECIFIED UNSPECIFIED Thuering, Johannes UNSPECIFIED UNSPECIFIED UNSPECIFIED Eysel, Peer UNSPECIFIED UNSPECIFIED UNSPECIFIED Hildebrand, Frank UNSPECIFIED UNSPECIFIED UNSPECIFIED Kobbe, Philipp UNSPECIFIED UNSPECIFIED UNSPECIFIED Scheyerer, Max Joseph UNSPECIFIED UNSPECIFIED UNSPECIFIED Herren, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-309368
DOI:	10.1016/j.clinbiomech.2020.105153
Journal or Publication Title:	Clin. Biomech.
Volume:	80
Date:	2020
Publisher:	ELSEVIER SCI LTD
Place of Publication:	OXFORD
ISSN:	1879-1271
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language BONE-MINERAL DENSITY; LUMBAR FUSION; RODS; BIOMATERIALS; IMPLANT Multiple languages Engineering, Biomedical; Orthopedics; Sport Sciences Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/30936